How to Train Your Dragon: Harnessing Gamma Delta T Cells Antiviral Functions and Trained Immunity in a Pandemic Era
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.666983
Abstract: The emergence of viruses with pandemic potential such as the SARS-CoV-2 coronavirus causing COVID-19 poses a global health challenge. There is remarkable progress in vaccine technology in response to this threat, but their design often… read more here.
Keywords: trained immunity; antiviral functions; gamma delta; delta cells ... See more keywords
Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner
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DOI: 10.3390/v15030646
Abstract: The innate immune system is the first line of host defense sensing viral infection. Manganese (Mn) has recently been found to be involved in the activation of the innate immune DNA-sensing cGAS-STING pathway and subsequent… read more here.
Keywords: manner; sting pathway; cgas sting; mn2 ... See more keywords
Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions
Sign Up to like & getrecommendations! Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8030369
Abstract: The innate DNA sensing receptors are one family of pattern recognition receptors and play important roles in antiviral infections, especially DNA viral infections. Among the multiple DNA sensors, cGAS has been studied intensively and is… read more here.
Keywords: sting signal; dna; antiviral functions; cgas sting ... See more keywords