α-Lipoic Acid Exerts Its Antiviral Effect against Viral Hemorrhagic Septicemia Virus (VHSV) by Promoting Upregulation of Antiviral Genes and Suppressing VHSV-Induced Oxidative Stress
Sign Up to like & getrecommendations! Published in 2021 at "Virologica Sinica"
DOI: 10.1007/s12250-021-00440-5
Abstract: Viral hemorrhagic septicemia virus (VHSV), belonging to the genus Novirhabdovirus, Rhabdoviridae family, is a causative agent of high mortality in fish and has caused significant losses to the aquaculture industry. Currently, no effective vaccines, Food… read more here.
Keywords: vhsv induced; septicemia virus; hemorrhagic septicemia; vhsv ... See more keywords
Relative mRNA Expression Levels of Restriction Factors and Antiviral Genes in Fetal and Adult Human Monocytes and Monocyte-Derived Macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0160
Abstract: Among untreated HIV-infected pregnant women, the frequency of mother-to-child transmission of HIV is low (5-10%), with most infections occurring at or after birth. Given findings that fetal and adult monocytes are distinct from one another… read more here.
Keywords: adult; fetal adult; expression; antiviral genes ... See more keywords
Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac513
Abstract: Abstract Antiviral innate immunity represents the first defense against invading viruses and is key to control viral infections, including SARS-CoV-2. Body temperature is an omnipresent variable but was neglected when addressing host defense mechanisms and… read more here.
Keywords: antiviral genes; temperature; body temperature; genes sars ... See more keywords
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
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DOI: 10.1371/journal.ppat.1008461
Abstract: The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters:… read more here.
Keywords: interferon alpha; induced antiviral; ifn induced; antiviral genes ... See more keywords