Design, synthesis and biological evaluation of gentiopicroside derivatives as potential antiviral inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.02.028
Abstract: Based on classical drug design theory, a novel series of gentiopicroside derivatives was designed and synthesized. All synthesized compounds were then biologically evaluated for their inhibition of influenza virus and anti-HCV activity in vitro. Some of… read more here.
Keywords: design synthesis; antiviral inhibitors; potential antiviral; synthesis biological ... See more keywords
Deciphering molecular properties and docking studies of hepatitis C and non‐hepatitis C antiviral inhibitors ‐ A computational approach
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.02.014
Abstract: Background: Hepatitis C is an infectious liver disease with high mortality rate which is caused by Hepatitis C virus. Several treatment methods have been applied to combat this deadly virus including interferons, vaccine and direct… read more here.
Keywords: properties docking; deciphering molecular; antiviral inhibitors; inhibitor ... See more keywords
Immunity Cell Responses to RSV and the Role of Antiviral Inhibitors: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s387479
Abstract: Abstract Antigen-presenting cells recognize respiratory syncytial virus antigens, and produce cytokines and chemokines that act on immune cells. Dendritic cells play the main role in inflammatory cytokine responses. Similarly, alveolar macrophages produce IFN-β, IFN-α, TNF-α,… read more here.
Keywords: syncytial virus; role; immunity cell; respiratory syncytial ... See more keywords