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Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03138-w
Abstract: While scientific advances have led to large-scale production and widespread distribution of vaccines and antiviral drugs, viruses still remain a major cause of human diseases today. The ever-increasing reports of viral resistance and the emergence…
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Keywords:
antiviral peptides;
therapeutic drugs;
peptides promising;
antimicrobial peptides ... See more keywords
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Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.3c00138
Abstract: Chemical control of protein activity is a powerful tool for scientific study, synthetic biology, and cell therapy; however, for broad use, effective chemical inducer systems must minimally crosstalk with endogenous processes and exhibit desirable drug…
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Keywords:
antiviral peptides;
controlled protein;
activity;
antiviral drugs ... See more keywords
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Published in 2022 at "Journal of bioinformatics and computational biology"
DOI: 10.1142/s0219720022500263
Abstract: In this study, we propose Feedback-AVPGAN, a system that aims to computationally generate novel antiviral peptides (AVPs). This system relies on the key premise of the Generative Adversarial Network (GAN) model and the Feedback method.…
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Keywords:
network;
antiviral peptides;
adversarial network;
feedback avpgan ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092619
Abstract: The marine environment presents a favorable avenue for potential therapeutic agents as a reservoir of new bioactive natural products. Due to their numerous potential pharmacological effects, marine-derived natural products—particularly marine peptides—have gained considerable attention. These…
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Keywords:
antiviral peptides;
peptides avps;
human viruses;
drug candidates ... See more keywords
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Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15061621
Abstract: The COVID-19 pandemic has made it clear that there is a crucial need for the design and development of antiviral agents that can efficiently reduce the fatality rate caused by infectious diseases. The fact that…
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Keywords:
cov hcov;
chitosan based;
antiviral peptides;
based nanoparticles ... See more keywords
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Published in 2023 at "Viruses"
DOI: 10.3390/v15040820
Abstract: Viruses with rapid replication and easy mutation can become resistant to antiviral drug treatment. With novel viral infections emerging, such as the recent COVID-19 pandemic, novel antiviral therapies are urgently needed. Antiviral proteins, such as…
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Keywords:
information;
antiviral peptides;
database;
proteins dravp ... See more keywords