Deception through Mimicry: A Cellular Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.11.033
Abstract: Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6… read more here.
Keywords: ebola virus; antiviral strategy; deception mimicry; cellular antiviral ... See more keywords
Sulfonamides: Antiviral Strategy for Neglected Tropical Disease Virus
Sign Up to like & getrecommendations! Published in 2020 at "Current Organic Chemistry"
DOI: 10.2174/1385272824999200515094100
Abstract: The viral infections are a threat to the health system around the globe. Although more than 60 antiviral drugs have been approved by the FDA, most of them are for the management of few viruses… read more here.
Keywords: tropical disease; antiviral strategy; sulfonamides antiviral; strategy neglected ... See more keywords
Current synopsis on siRNA therapeutics as a novel anti-cancer and antiviral strategy: Progress and challenges.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201023666220516120432
Abstract: Currently, a popular era in nanomedicine is the implementation of RNA nanoparticles for various diseases and their diagnosis. RNA interference (RNAi) involves the arrangement of gene mediating mechanisms where coding and non-coding are carried out.… read more here.
Keywords: anti cancer; antiviral strategy; sirna; cancer antiviral ... See more keywords
Unlocking STING as a Therapeutic Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087448
Abstract: Invading pathogens have developed weapons that subvert physiological conditions to weaken the host and permit the spread of infection. Cells, on their side, have thus developed countermeasures to maintain cellular physiology and counteract pathogenesis. The… read more here.
Keywords: antiviral strategy; physiology; therapeutic antiviral; sting therapeutic ... See more keywords
CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10010040
Abstract: Currently, a new gene editing tool—the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated (Cas) system—is becoming a promising approach for genetic manipulation at the genomic level. This simple method, originating from the adaptive immune… read more here.
Keywords: genes antiviral; antiviral strategy; crispr cas; cas ... See more keywords
Efficient CRISPR-Cas13d-Based Antiviral Strategy to Combat SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15030686
Abstract: The current SARS-CoV-2 pandemic forms a major global health burden. Although protective vaccines are available, concerns remain as new virus variants continue to appear. CRISPR-based gene-editing approaches offer an attractive therapeutic strategy as the CRISPR-RNA… read more here.
Keywords: antiviral strategy; crispr cas13d; strategy; sars cov ... See more keywords