Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
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DOI: 10.1007/s10753-021-01555-3
Abstract: One type of age-related macular degeneration (AMD), neovascular (nAMD), characterized by choroidal neovascularization (CNV), accounts for the majority of the severe central vision impairment associated with AMD. Endothelial cells (ECs) in direct contact with retinal… read more here.
Keywords: inflammasome pyroptosis; pyroptosis; axis; rpe cells ... See more keywords
Anti-inflammatory Annexin A1 in Periodontitis via Formyl Peptide Receptor 2
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DOI: 10.1177/00220345251322151
Abstract: Although annexin A1 (ANXA1) is known to mediate inflammatory responses through N-formyl peptide receptor 2 (FPR2), the role of the ANXA1-FPR2 signaling pathway in periodontal disease remains unclear. This study investigated the contribution of this… read more here.
Keywords: inflammatory; peptide receptor; formyl peptide; anxa1 fpr2 ... See more keywords