Co-administration of nalbuphine attenuates the morphine-induced anxiety and dopaminergic alterations in morphine-withdrawn rats.
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DOI: 10.1007/s00213-021-05765-3
Abstract: INTRODUCTION The classical effects of exogenous opioids, such as morphine, are predominantly mediated through μ-opioid receptors. The chronic use of morphine induces anxiety-like behavior causing functional changes in the mesolimbic dopaminergic system. The mixed μ/κ-agonist,… read more here.
Keywords: morphine induced; morphine; induced anxiety; anxiety ... See more keywords