Gasotransmitter‐Nanodonor for Spatial Regulation of Anxiety‐Like Behavior and Bone Metastasis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202416481
Abstract: Anxiety is highly prevalent among cancer patients, significantly impacting their prognosis. Current cancer therapies typically lack anxiolytic properties and may even exacerbate anxiety. Here, a gasotransmitter‐nanodonors (GND) system is presented that exerts dual anxiolytic and… read more here.
Keywords: anxiety like; gasotransmitter nanodonor; like behavior; tumor ... See more keywords
Propofol Alleviates Anxiety‐Like Behaviors Associated with Pain by Inhibiting the Hyperactivity of PVNCRH Neurons via GABAA Receptor β3 Subunits
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202309059
Abstract: Pain, a comorbidity of anxiety disorders, causes substantial clinical, social, and economic burdens. Emerging evidence suggests that propofol, the most commonly used general anesthetic, may regulate psychological disorders; however, its role in pain‐associated anxiety is… read more here.
Keywords: anxiety like; like behaviors; pvncrh neurons; pain ... See more keywords
A behavioral and molecular study; ameliorated anxiety‐like behavior and cognitive dysfunction in a rat model of chronic unpredictable stress treated with oregano extract
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2727
Abstract: Chronic stress is considered a severe risk factor leading to various disorders, including anxiety and cognitive decline. The present study aimed to investigate the effects of Origanum vulgare (oregano) extract on improving anxiety‐like behavior and… read more here.
Keywords: stress; anxiety like; oregano extract; chronic unpredictable ... See more keywords
Maternal nicotine intoxication before pregnancy induces depressive- and anxiety-like behaviors as well as cognitive deficits in male offspring and correlates with neurobiological changes.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3052
Abstract: INTRODUCTION Maternal nicotine use has been suggested to affect the behavior of children and is linked to changes in neurological systems; however, the specific mechanism is yet to be understood. METHODS Mice were used to… read more here.
Keywords: anxiety like; male offspring; nicotine intoxication; maternal nicotine ... See more keywords
Tuina Alleviates Anxiety‐Like Behaviors Associated With Neuropathic Pain Through the Modulation of Synaptic Plasticity in the Anterior Cingulate Cortex
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70965
Abstract: As the disease progresses, neuropathic pain (NP) is often accompanied by anxiety‐like behaviors, which are associated with plastic changes in the synaptic structure and function within the anterior cingulate cortex (ACC). Tuina is a traditional… read more here.
Keywords: anxiety like; like behaviors; anterior cingulate; neuropathic pain ... See more keywords
Sex and age differences in locomotor and anxiety-like behaviors in rats: From adolescence to adulthood.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental psychobiology"
DOI: 10.1002/dev.22037
Abstract: Risk-taking behaviors are a primary contributor to elevated adolescent injury and mortality. Locomotor and anxiety-like behaviors in rodents have been used to examine risk-taking. Here, we examined risk-taking behavior (i.e., changes in locomotor and anxiety-like… read more here.
Keywords: anxiety; locomotor anxiety; adolescence; anxiety like ... See more keywords
Environmental enrichment decreases anxiety‐like behavior in zebrafish larvae
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Psychobiology"
DOI: 10.1002/dev.22255
Abstract: Abstract The development of anxiety disorders is often linked to individuals’ negative experience. In many animals, development of anxiety‐like behavior is modeled by manipulating individuals’ exposure to environmental enrichment. We investigated whether environmental enrichment during… read more here.
Keywords: anxiety like; environmental enrichment; larvae; like behavior ... See more keywords
Dammarane sapogenins attenuates stress‐induced anxiety‐like behaviors by upregulating ERK/CREB/BDNF pathways
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6713
Abstract: Dammarane sapogenins (DS), an extract derived from ginseng by alkaline hydrolysis of total ginsenosides, possesses high pharmacological activity and higher bioavailability than ginsenosides. The present study was designed to investigate the anxiolytic‐like effects of DS… read more here.
Keywords: creb bdnf; anxiety like; creb; erk creb ... See more keywords
Cyanobacterial extract with serotonin receptor subtype 7 (5‐HT7R) affinity modulates depression and anxiety‐like behavior in mice
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DOI: 10.1002/syn.22059
Abstract: Marine cyanobacteria represent a unique source in the field of drug discovery due to the secondary metabolites they produce and the structural similarity these compounds have to endogenous mammalian receptor ligands. A series of cyanobacteria… read more here.
Keywords: ht7r; affinity; anxiety like; receptor ... See more keywords
Effects of treadmill exercise and chronic stress on anxiety‐like behavior, neuronal activity, and oxidative stress in basolateral amygdala in morphine‐treated rats
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DOI: 10.1002/syn.22256
Abstract: The basolateral amygdala (BLA), which is sensitive to stress, is necessary for reward‐seeking behavior and addiction. Regular exercise can produce various positive effects by affecting the BLA. Therefore, we aimed to investigate the effects of… read more here.
Keywords: stress; anxiety like; behavior neuronal; like behavior ... See more keywords
Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23545
Abstract: Parabens are synthetic antimicrobial compounds used as a preservative for extending the shelf life of food, pharmaceutical and cosmetic products. The alkyl chain length of the paraben esters positively correlates with their antimicrobial property. Hence,… read more here.
Keywords: zebrafish larvae; anxiety like; butylparaben propylparaben; apoptosis ... See more keywords