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Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05699-7
Abstract: Echium amoenum (EA), a popular medicinal plant in Persian medicine, has anxiolytic, antioxidant, sedative, and anti-inflammatory effects. This study examined whether GABA-ergic signaling is involved in the anxiolytic effects of EA in mice. Sixty BALB/c… read more here.
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Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2016.10.010
Abstract: Graphical abstract Figure. No Caption available. HighlightsNAC shows anxiolytic effects on five mice models of anxiety.Subacute NAC results in lower effective anxiolytic doses than acute treatment.Anxiolytic doses of NAC do not affect locomotion. ABSTRACT Anxiety… read more here.
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Published in 2021 at "Journal of Traditional and Complementary Medicine"
DOI: 10.1016/j.jtcme.2021.07.004
Abstract: Abstract Schinus lentiscifolius (Anacardiaceae) is widely used in folk medicine for treating gastrointestinal and emotional complaints but there are no scientific studies that support these uses. This work aims at evaluating the antispasmodic and central… read more here.
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Published in 2022 at "Planta Medica"
DOI: 10.1055/a-2058-3710
Abstract: Abstract Rauvolfia species are well known as producers of bioactive monoterpene indole alkaloids, which exhibit a broad spectrum of biological activities. A new vobasine-sarpagan-type bisindole alkaloid ( 1 ) along with six known monomeric indoles… read more here.
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Published in 2017 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.13965
Abstract: Neurosteroids are synthesized in the nervous system from cholesterol or steroidal precursors imported from peripheral sources. These compounds are important allosteric modulators of GABAA receptors, which play a vital role in modulating hippocampal functions. Chronic… read more here.
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Published in 2023 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2023-0022
Abstract: Abstract The vestibular system inhibits both HPA and SAM axis and contributes to the management of anxiety. Both direct and indirect pathways exist in the inhibition of the HPA and SAM axis. In this review… read more here.
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Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00494
Abstract: Latua pubiflora (Griseb) Phil. Is a native shrub of the Solanaceae family that grows freely in southern Chile and is employed among Mapuche aboriginals to induce sedative effects and hallucinations in religious or medicine rituals… read more here.
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Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092104
Abstract: Background: Neurotensin (NT) acts as a neurotransmitter and neuromodulator in the central nervous system. It was shown previously that NT in the ventral pallidum (VP) has rewarding and anxiolytic effects. NT exerts its effect in… read more here.
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Published in 2022 at "Behavioral Sciences"
DOI: 10.3390/bs12070235
Abstract: Alzheimer’s disease (AD) significantly impairs the life of an individual both cognitively and behaviorally. Tau and beta-amyloid (Aβ) proteins are major contributors to the etiology of AD. This study used mice modeling AD through the… read more here.