Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice
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DOI: 10.1371/journal.pone.0227165
Abstract: Aim Abdominal aortic aneurysms (AAA) is a life-threatening weakening and expansion of the abdominal aorta due to inflammatory cell infiltration and gradual degeneration of extracellular matrix (ECM). There are no pharmacological therapies to treat AAA.… read more here.
Keywords: elastase; elastase induced; pentagalloyl glucose; abdominal aortic ... See more keywords