Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.
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DOI: 10.1172/jci.insight.168793
Abstract: To improve our limited understanding of the pathogenesis of thoracic aortic aneurysm (TAA) leading to acute aortic dissection, single-cell RNA sequencing (scRNA-seq) was employed to profile disease-relevant transcriptomic changes of aortic cell populations in a… read more here.
Keywords: cell; marfan syndrome; taa; aortic aneurysm ... See more keywords