Oxymatrine ameliorates diabetes‐induced aortic endothelial dysfunction via the regulation of eNOS and NOX4
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28006
Abstract: Oxymatrine (OMT) is the major quinolizidine alkaloid extracted from the root of Sophora flavescens Ait (the Chinese herb Kushen) and exhibits diverse pharmacological actions. In this study, we investigated the effects of OMT on diabetes‐associated… read more here.
Keywords: ameliorates diabetes; oxymatrine ameliorates; diabetes induced; endothelial dysfunction ... See more keywords
Effects of Taurine on Broiler Aortic Endothelial Cells Activity and Antioxidant Ability Impired by Heat Stress In Vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_59
Abstract: In order to provide a theoretical basis for the amelioration of heat stress-related diseases in broilers by taurine supplementation, the effect of taurine on the viability and antioxidant ability of aortic endothelial cells in broilers… read more here.
Keywords: heat stress; group; endothelial cells; activity ... See more keywords
Asiatic acid stabilizes cytoskeletal proteins and prevents TNF-α-induced disorganization of cell-cell junctions in human aortic endothelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2018.08.005
Abstract: Endothelial hyperpermeability represents an initiating step in early atherosclerosis and it often occurs as a result of endothelial barrier dysfunction. Asiatic acid, a major triterpene isolated from Centella asiatica (L.) Urban, has previously been demonstrated… read more here.
Keywords: tnf induced; aortic endothelial; asiatic acid; acid ... See more keywords
Long noncoding RNA UC.98 stabilizes atherosclerotic plaques by promoting the proliferation and adhesive capacity in murine aortic endothelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmz155
Abstract: Pathological studies have shown that the vulnerability of plaques affects outcomes in patients with atherosclerosis (AS), a chronic inflammatory disease and common cause of morbidity and mortality worldwide. Although emerging technologies have enabled early diagnosis… read more here.
Keywords: long noncoding; atherosclerotic plaques; noncoding rna; murine aortic ... See more keywords
Deletion of METTL14, a key methylation regulator, attenuates vascular ageing
Sign Up to like & getrecommendations! Published in 2025 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehaf476
Abstract: Abstract Background and Aims Vascular ageing often accompanies inflammation, contributing to the onset of local or systemic vascular diseases. Nevertheless, limited research focuses on pivotal factors triggering chronic vascular inflammation and associated pathological changes. This… read more here.
Keywords: mettl14 key; mettl14; aortic endothelial; deletion mettl14 ... See more keywords
Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Xenotransplantation"
DOI: 10.1111/xen.12537
Abstract: After hyperacute rejection in pig‐to‐primate xenotransplantation had been overcome by the introduction of α1,3‐galactosyltransferase gene‐knockout (GTKO) pigs, acute and chronic antibody‐mediated rejection became one of the major barriers to long‐term graft survival. This was associated… read more here.
Keywords: porcine aortic; antibody; endothelial cells; antibody binding ... See more keywords
Direct Effects of Waterpipe Smoke Extract on Aortic Endothelial Cells: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2025 at "Physiological Research"
DOI: 10.33549/physiolres.935409
Abstract: Summary Waterpipe smoking (WPS) has adverse health effects that include endothelial dysfunction with mechanisms involving oxidative stress and inflammation. Nonetheless, there is a scarcity of data on the direct impact of WPS on endothelial function.… read more here.
Keywords: waterpipe smoke; aortic endothelial; effects waterpipe; smoke extract ... See more keywords
Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.845918
Abstract: Endoglin (Eng) is a co-receptor of the transforming growth factor β superfamily playing an important role in endothelial dysfunction. TRC105 (carotuximab) is a monoclonal antibody that blocks Eng and its downstream Smad signaling pathway. Here… read more here.
Keywords: trc105 carotuximab; dysfunction; hyperglycemia; human aortic ... See more keywords
Chamazulene Attenuates ROS Levels in Bovine Aortic Endothelial Cells Exposed to High Glucose Concentrations and Hydrogen Peroxide
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00246
Abstract: Endothelial cells surround the lumen of blood vessels and modulate many physiological processes, including vascular tone, blood fluidity, inflammation, immunity and neovascularization. Many pathological conditions, including hyperglycemia, may alter endothelial function through oxidative stress, leading… read more here.
Keywords: bovine aortic; levels bovine; high glucose; endothelial cells ... See more keywords
Blueberry Polyphenols Increase Nitric Oxide and Attenuate Angiotensin II-Induced Oxidative Stress and Inflammatory Signaling in Human Aortic Endothelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11040616
Abstract: Accumulating evidence indicate that blueberries have anti-hypertensive properties, which may be mainly due to its rich polyphenol content and their high antioxidant capacity. Thus, we aimed to investigate the mechanisms by which blueberry polyphenols exert… read more here.
Keywords: blueberry polyphenols; human aortic; increase; oxidative stress ... See more keywords
Polyunsaturated Fatty Acid (PUFA) Composition of Growth Medium Changes the Atherogenic Potential of Human Aortic Endothelial Cells (HAECs) Following Endotoxin Stimulation
Sign Up to like & getrecommendations! Published in 2025 at "Biomedicines"
DOI: 10.3390/biomedicines13112706
Abstract: Background/Objectives: Endothelial activation by lipopolysaccharides (LPS) contributes to inflammation and the development of cardiovascular disease, making n-3 polyunsaturated fatty acids (PUFAs) potential modulators capable of mitigating endothelial dysfunction. The current study examines the effects of… read more here.
Keywords: human aortic; aortic endothelial; polyunsaturated fatty; medium ... See more keywords