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Published in 2025 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.5c00628
Abstract: Vascular Ehlers-Danlos syndrome (vEDS) is a rare connective tissue disorder caused by mutations in the COL3A1 gene, leading to life-threatening vascular complications. This study presents a proteomic analysis of aortic wall tissue from a 60…
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Keywords:
aortic tissue;
vascular ehlers;
ehlers danlos;
danlos syndrome ... See more keywords
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Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4361339
Abstract: Background: Inflammatory signaling and extracellular matrix (ECM) remodeling play crucial roles in the formation of thoracic aortic aneurysms (TAAs). D-series Resolvins, including Resolvin D2 (RvD2), are endogenous pro-resolving mediators that promote anti-inflammatory signaling and effectively…
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Keywords:
aortic tissue;
mice;
abstract 4361339;
rvd2 ... See more keywords
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Published in 2022 at "Reviews in cardiovascular medicine"
DOI: 10.31083/j.rcm2302047
Abstract: BACKGROUND The limitation of aortic size-based criteria is gradually recognized in the prediction of aortic events especially in bicuspid aortic valve (BAV) cohorts, while most aortic events happen in patients with proximal aortic diameters
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Keywords:
mir;
circulating micrornas;
blood aortic;
aortic tissue ... See more keywords
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Published in 2024 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1305128
Abstract: Vascular diseases, such as abdominal aortic aneurysms, are associated with tissue degeneration of the aortic wall, resulting in variations in mechanical properties, such as tissue ultimate stress and a high slope. Variations in the mechanical…
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Keywords:
mechanical properties;
aortic tissue;
group;
collagen cross ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010315
Abstract: Perlecan (HSPG2), a basement membrane-type heparan sulfate proteoglycan, has been implicated in the development of aortic tissue. However, its role in the development and maintenance of the aortic wall remains unknown. Perlecan-deficient mice (Hspg2−/−-Tg: Perl…
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Keywords:
aortic tissue;
risk;
aortic dissection;
perlecan deficiency ... See more keywords