Genome-wide identification and analysis of AP2/ERF transcription factors related to camptothecin biosynthesis in Camptotheca acuminata.
Sign Up to like & getrecommendations! Published in 2020 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(20)30070-4
Abstract: Camptotheca acuminata produces camptothecin (CPT), a monoterpene indole alkaloid (MIA) that is widely used in the treatment of lung, colorectal, cervical, and ovarian cancers. Its biosynthesis pathway has attracted significant attention, but the regulation of… read more here.
Keywords: biosynthesis; cacap2; analysis; ap2 ... See more keywords
FCHO controls AP2’s initiating role in endocytosis through a PtdIns(4,5)P2-dependent switch
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn2018
Abstract: Clathrin-mediated endocytosis (CME) is the main mechanism by which mammalian cells control their cell surface proteome. Proper operation of the pivotal CME cargo adaptor AP2 requires membrane-localized Fer/Cip4 homology domain-only proteins (FCHO). Here, live-cell enhanced… read more here.
Keywords: fcho controls; controls ap2; initiating role; endocytosis ... See more keywords
CDK5 inhibits the clathrin-dependent internalization of TRPV1 by phosphorylating the clathrin adaptor protein AP2μ2
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DOI: 10.1126/scisignal.aaw2040
Abstract: CDK5 inhibits constitutive internalization of the nociceptor TRPV1 and contributes to inflammatory hyperalgesia. Constitutive internalization of a nociceptor The nonselective cation channel TRPV1 elicits the sensation of burning pain in response to thermal or chemical… read more here.
Keywords: trpv1; adaptor protein; internalization; ap2 ... See more keywords
AP2 Regulates Thickveins Trafficking to Attenuate NMJ Growth Signaling in Drosophila
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DOI: 10.1523/eneuro.0044-22.2022
Abstract: Abstract Compromised endocytosis in neurons leads to synapse overgrowth and altered organization of synaptic proteins. However, the molecular players and the signaling pathways which regulate the process remain poorly understood. Here, we show that σ2-adaptin,… read more here.
Keywords: ap2 regulates; growth; thickveins trafficking; regulates thickveins ... See more keywords
Genome-Wide Identification and Expression Analysis of AP2/ERF Transcription Factor Related to Drought Stress in Cultivated Peanut (Arachis hypogaea L.)
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DOI: 10.3389/fgene.2021.750761
Abstract: APETALA2/ethylene response element-binding factor (AP2/ERF) transcription factors (TFs) have been found to regulate plant growth and development and response to various abiotic stresses. However, detailed information of AP2/ERF genes in peanut against drought has not… read more here.
Keywords: analysis; ap2; peanut; element binding ... See more keywords
Genome-wide investigation of AP2/ERF gene family in the desert legume Eremosparton songoricum: Identification, classification, evolution, and expression profiling under drought stress
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DOI: 10.3389/fpls.2022.885694
Abstract: Eremosparton songoricum (Litv.) Vass. is a rare leafless legume shrub endemic to central Asia which grows on bare sand. It shows extreme drought tolerance and is being developed as a model organism for investigating morphological,… read more here.
Keywords: stress; ap2 erf; ap2; classification ... See more keywords
Genome-Wide Analysis of AP2/ERF Gene Superfamily in Ramie (Boehmeria nivea L.) Revealed Their Synergistic Roles in Regulating Abiotic Stress Resistance and Ramet Development
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DOI: 10.3390/ijms232315117
Abstract: AP2/ERF transcription factors (TFs) are one of the largest superfamilies in plants, and play vital roles in growth and response to biotic/abiotic stresses. Although the AP2/ERF family has been extensively characterized in many species, very… read more here.
Keywords: ramet development; stress; ap2 erf; ap2 ... See more keywords