Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites
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DOI: 10.1371/journal.ppat.1010887
Abstract: Plasmodium parasites are reliant on the Apicomplexan AP2 (ApiAP2) transcription factor family to regulate gene expression programs. AP2 DNA binding domains have no homologs in the human or mosquito host genomes, making them potential antimalarial… read more here.
Keywords: plasmodium parasites; ap2 exp; plasmodium; dna binding ... See more keywords