Apamin inhibits renal fibrosis via suppressing TGF-β1 and STAT3 signaling in vivo and in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular medicine"
DOI: 10.1007/s00109-021-02087-x
Abstract: Renal fibrosis is a progressive and chronic process that influences kidneys with chronic kidney disease (CKD), irrespective of cause, leading to irreversible failure of renal function and end-stage kidney disease. Among the signaling related to… read more here.
Keywords: fibrosis; renal fibrosis; activation; induced renal ... See more keywords
Protective Effects of Apamin on Acetaminophen-Induced Hepatotoxicity in Mice
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DOI: 10.3390/cimb45050279
Abstract: Acetaminophen (APAP) overdose can cause severe liver damage, but therapeutic options are limited. Apamin is a natural peptide present in bee venom and has antioxidant and anti-inflammatory properties. Accumulating evidence suggests that apamin has favorable… read more here.
Keywords: protective effects; apamin; apamin acetaminophen; acetaminophen induced ... See more keywords
Novel Nanoconjugate of Apamin and Ceftriaxone for Management of Diabetic Wounds
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12071096
Abstract: Diabetic hyperglycemia delays wound healing, leading to serious consequences. Topical antibiotics can reduce the risk of a wound infection during healing; nevertheless, the microbial fight against antibiotics brings about public health challenges. Anti-microbial peptides (AMPs)… read more here.
Keywords: apamin; ctx apa; apa; factor ... See more keywords