CoQ10 protects against acetaminophen-induced liver injury by enhancing mitophagy.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115355
Abstract: Coenzyme Q10 (CoQ10), which is a key cofactor of the electron transport chain in the mitochondria has shown many beneficial effects on liver diseases. However, the mechanisms of CoQ10 protective role on the acetaminophen (APAP)-induced… read more here.
Keywords: induced liver; treatment; coq10; apap overdose ... See more keywords
Role of extracellular vesicles in release of protein adducts after acetaminophen-induced liver injury in mice and humans.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.11.005
Abstract: Formation of acetaminophen (APAP) protein adducts are a critical feature of APAP hepatotoxicity, and circulating protein adducts have recently been utilized in bioassays for identification of APAP overdose in humans. Despite their clinical significance, mechanisms… read more here.
Keywords: protein adducts; apap overdose; release; apap protein ... See more keywords