Articles with "apatinib motesanib" as a keyword



Effects of multi-kinase inhibitors on the activity of cytochrome P450 2J2

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Published in 2022 at "Xenobiotica"

DOI: 10.1080/00498254.2022.2137068

Abstract: Abstract 1. Cytochrome P450 2J2 (CYP2J2) shows high expression in extrahepatic tissues, including the heart and kidney and in tumours. Inhibition of CYP2J2 has attracted attention for cancer treatment because it metabolises arachidonic acid (AA)… read more here.

Keywords: p450 2j2; cytochrome p450; apatinib motesanib; activity ... See more keywords