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Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029412
Abstract: RATIONALE PTTM is a rare but fatal disease, characterized by endothelial intimal proliferation and pulmonary hypertension due to micro-vascular remodeling. In view of the poor prognosis, new effective strategies are urgently required. PATIENT CONCERNS AND…
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Keywords:
pulmonary hypertension;
hypertension;
therapy;
case report ... See more keywords
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Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13806
Abstract: Apatinib, an oral antiangiogenic drug, exerts potential anti‐tumour effects on platinum‐resistant recurrent ovarian cancer (PROC). This study intended to evaluate the efficacy and safety of apatinib plus paclitaxel compared to paclitaxel monotherapy in PROC patients.
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Keywords:
recurrent ovarian;
platinum resistant;
ovarian cancer;
apatinib plus ... See more keywords
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Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3009494
Abstract: Objective To evaluate the efficacy of low dose apatinib plus chemotherapy on advanced gastric carcinoma. Methods Eligible 50 patients with advanced gastric carcinoma admitted to the hospital from January 2019 to March 2020 were enrolled,…
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Keywords:
plus chemotherapy;
advanced gastric;
apatinib plus;
group ... See more keywords
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Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/4322404
Abstract: Background Apatinib is established to be the standard of care as third-line therapy for patients with previously treated advanced gastric cancer (GC). Programmed cell death protein 1 (PD-1) blockades also exhibited promising efficacy and safety…
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Keywords:
treated advanced;
plus inhibitors;
previously treated;
apatinib plus ... See more keywords
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Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e13096
Abstract: e13096Background: Antiangiogenic therapy in combination with chemotherapy is effective in control advanced breast cancer. Apatinib is an oral highly potent tyrosine kinase inhibitor targeting vascu...
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Keywords:
combination;
apatinib plus;
cancer apatinib;
breast cancer ... See more keywords
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Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.1075
Abstract: 1075 Background: No standard treatment exists for triple negative breast cancer (TNBC) with failure of multi-line therapies. Apatinib is a small-molecule tyrosine kinase inhibitor that has promising anti-angiogenesis and antitumor activity for TNBC. We aimed…
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Keywords:
line;
treatment;
plus vinorelbine;
apatinib plus ... See more keywords
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Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e16132
Abstract: e16132 Background: A variety of staged hepatic resection has been applied in patients (pts) with hepatocellular carcinoma (HCC) who had an inadequate future-remnant-liver (FRL), but the clinical outcomes remain unsatisfactory. Based on the clinical data…
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Keywords:
hepatocellular carcinoma;
plus camrelizimab;
treatment;
apatinib plus ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.835889
Abstract: Objective This study was conducted in order to compare the efficacy and safety of transarterial chemoembolization (TACE) plus apatinib plus camrelizumab (TACE+AC) and apatinib plus camrelizumab (AC) in the treatment of unresectable hepatocellular carcinoma (HCC)…
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Keywords:
hepatocellular carcinoma;
plus camrelizumab;
apatinib plus;
group ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.952494
Abstract: Background Both apatinib and programmed death 1 (PD-1) monoclonal antibody (mAb) monotherapy have been licensed in China for the third-line treatment of advanced gastric cancer (AGC). However, whether the combination could improve the prognosis of…
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Keywords:
apatinib;
apatinib plus;
monotherapy;
plus mab ... See more keywords
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Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1072943
Abstract: Objective Apatinib and irinotecan are used as systematic therapies for advanced gastric adenocarcinoma (GAC) and gastroesophageal junction adenocarcinoma (GEJA), while the evidence for their combination as second-line therapy in these patients is limited. This study…
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Keywords:
apatinib;
apatinib plus;
second line;
treatment ... See more keywords
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Published in 2022 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_1853_21
Abstract: Background: Anti-angiogenesis drugs are applicable in treating advanced non-small cell lung cancer (NSCLC); however, the related data regarding apatinib, a Chinese domestic anti-vascular endothelial growth factor receptor-2 (VEGFR-2) production, are limited. Therefore, this study explored…
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Keywords:
apatinib plus;
plus platinum;
doublet chemotherapy;
platinum doublet ... See more keywords