Conformational Selection Mechanism Provides Structural Insights into the Optimization of APC-Asef Inhibitors
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DOI: 10.3390/molecules26040962
Abstract: Metastasis is the major cause of death in colorectal cancer and it has been proven that inhibiting an interaction between adenomatous polyposis coli (APC) and Rho guanine nucleotide exchange factor 4 (Asef) efficaciously restrain metastasis.… read more here.
Keywords: selection mechanism; apc asef; mechanism; insights optimization ... See more keywords