Human MAIT cells are rapidly activated by Aspergillus spp. in an APC‐dependent manner
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DOI: 10.1002/eji.201747312
Abstract: Mucosal associated invariant T cells (MAIT cells) are innate‐like T cells (TC) which are known to be activated by several bacteria and viruses. However, activation of MAIT cells by moulds, such as the opportunistic human… read more here.
Keywords: mait cells; dependent manner; mait; apc dependent ... See more keywords
Examining the mechanistic relationship of APC/CCDH1 and its interphase inhibitor EMI1
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DOI: 10.1002/pro.4324
Abstract: Proper protein destruction by the ubiquitin (Ub)‐proteasome system is vital for a faithful cell cycle. Hence, the activity of Ub ligases is tightly controlled. The Anaphase‐Promoting Complex/Cyclosome (APC/C) is a 1.2 MDa Ub ligase responsible for… read more here.
Keywords: emi1; relationship apc; mechanistic relationship; apc dependent ... See more keywords
APC/C‐dependent degradation of Spd2 regulates centrosome asymmetry in Drosophila neural stem cells
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DOI: 10.15252/embr.202255607
Abstract: A functional centrosome is vital for the development and physiology of animals. Among numerous regulatory mechanisms of the centrosome, ubiquitin‐mediated proteolysis is known to be critical for the precise regulation of centriole duplication. However, its… read more here.
Keywords: neural stem; spd2; apc dependent; degradation ... See more keywords