Implications of alternative routes to APC/C inhibition by the mitotic checkpoint complex
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DOI: 10.1371/journal.pcbi.1006449
Abstract: The mitotic checkpoint (also called spindle assembly checkpoint) is a signaling pathway that ensures faithful chromosome segregation. Mitotic checkpoint proteins inhibit the anaphase-promoting complex (APC/C) and its activator Cdc20 to prevent precocious anaphase. Checkpoint signaling… read more here.
Keywords: implications alternative; alternative routes; apc inhibition; checkpoint ... See more keywords