Abstract PS16-23: Elucidating the role of APC resulting in doxorubicin resistance in breast cancer
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DOI: 10.1158/1538-7445.sabcs20-ps16-23
Abstract: Chemoresistance is a leading cause of breast cancer related deaths. Therefore, understanding the molecularbasis for chemoresistance is essential for novel therapeutic advancement improving patient outcome. TheAdenomatous Polyposis Coli (APC) tumor suppressor is lost in up… read more here.
Keywords: breast cancer; apc min; apc loss; cancer ... See more keywords
Rapamycin Liposomes Combined with 5-Fluorouracil Inhibits Angiogenesis and Tumor Growth of APC (Min/+) Mice and AOM/DSS-Induced Colorectal Cancer Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s373777
Abstract: Background Transgenic C57BL/6-APC(Min/+) spontaneous cancer mouse model and the Azoxymethane (AOM)/Dextran Sulfate Sodium (DSS) chemically induced orthotopic colorectal cancer mouse model represented distinct pathogenesis of colorectal cancers. Our previous study revealed that the combination of… read more here.
Keywords: rapa lps; aom; apc min; colorectal cancer ... See more keywords