Molecular drivers of tumor progression in microsatellite stable APC mutation-negative colorectal cancers
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DOI: 10.1038/s41598-021-02806-x
Abstract: The tumor suppressor gene adenomatous polyposis coli (APC) is the initiating mutation in approximately 80% of all colorectal cancers (CRC), underscoring the importance of aberrant regulation of intracellular WNT signaling in CRC development. Recent studies… read more here.
Keywords: mutation negative; microsatellite stable; colorectal cancers; mutation ... See more keywords