Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma
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DOI: 10.1136/gutjnl-2022-327076
Abstract: Objective Oesophageal adenocarcinoma (EAC) arises in the setting of Barrett’s oesophagus, an intestinal metaplastic precursor lesion that can develop in patients with chronic GERD. Here, we investigated the role of acidic bile salts, the mimicry… read more here.
Keywords: notch signaling; ape1 redox; dll1; notch ... See more keywords