Lack of defined apheresis collection criteria in publicly available CAR-T cell clinical trial descriptions: Comprehensive review of over 600 studies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical apheresis"
DOI: 10.1002/jca.21964
Abstract: BACKGROUND Chimeric antigen receptor T (CAR-T) cell successes have encouraged continued clinical study. Apheresis collection of starting material for CAR-T cell therapy product manufacturing is critical but described approaches suggest variability and clinical guidelines are… read more here.
Keywords: apheresis collection; apheresis; car cell; cell ... See more keywords
Optimizing haematopoietic stem and progenitor cell apheresis collection from plerixafor‐mobilized patients with sickle cell disease
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DOI: 10.1111/bjh.18311
Abstract: We adjusted haematopoietic stem and progenitor cell (HSPC) apheresis collection from patients with sickle cell disease (SCD) by targeting deep buffy coat collection using medium or low collection preference (CP), and by increasing anticoagulant–citrate–dextrose–solution A… read more here.
Keywords: cell; haematopoietic stem; progenitor cell; stem progenitor ... See more keywords
Comparison of platelet quality and function across apheresis collection platforms
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DOI: 10.1111/trf.17370
Abstract: Platelet concentrates (PLT) can be manufactured using a combination of apheresis collection devices and suspension media (plasma or platelet additive solution (PAS)). It is unclear how platelet quality and hemostatic function differ across the current… read more here.
Keywords: function; apheresis; apheresis collection; collection platforms ... See more keywords