The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e22-09-0411
Abstract: Apical constriction results in apical surface reduction in epithelial cells and is a widely used mechanism for epithelial morphogenesis. Both medioapical and junctional actomyosin remodeling are involved in apical constriction, but the deployment of medial… read more here.
Keywords: apical constriction; media see; junctional actomyosin; see text ... See more keywords
Apical constriction requires patterned apical surface remodeling to synchronize cellular deformation
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DOI: 10.1101/2023.12.19.572310
Abstract: Apical constriction is a basic mechanism for epithelial morphogenesis, making columnar cells into wedge shape and bending a flat cell sheet. It has long been thought that an apically localized myosin generates a contractile force… read more here.
Keywords: apical surface; deformation; constriction; shape ... See more keywords
The Ajuba family protein Wtip regulates actomyosin contractility during vertebrate neural tube closure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.213884
Abstract: ABSTRACT Ajuba family proteins are implicated in the assembly of cell junctions and have been reported to antagonize Hippo signaling in response to cytoskeletal tension. To assess the role of these proteins in actomyosin contractility,… read more here.
Keywords: wtip; apical constriction; neural tube; ajuba family ... See more keywords
Zyxin contributes to coupling between cell junctions and contractile actomyosin networks during apical constriction
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010319
Abstract: One of the most common cell shape changes driving morphogenesis in diverse animals is the constriction of the apical cell surface. Apical constriction depends on contraction of an actomyosin network in the apical cell cortex,… read more here.
Keywords: cell; apical constriction; actomyosin networks; cell junctions ... See more keywords
Evidence for a Role of the Lateral Ectoderm in Drosophila Mesoderm Invagination
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.867438
Abstract: The folding of two-dimensional epithelial sheets into specific three-dimensional structures is a fundamental tissue construction mechanism in animal development. A common mechanism that mediates epithelial folding is apical constriction, the active shrinking of cell apices… read more here.
Keywords: drosophila mesoderm; mesoderm invagination; invagination; apical constriction ... See more keywords
Comparative evaluation of apical constriction position in incisor and molar teeth: An in vitro study
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DOI: 10.4103/ejd.ejd_54_18
Abstract: Objective: The apical constriction (AC) and the apical foramen (AF) are the principal reference points used to determine the apical limit for instrumentation and root canal filling. AC varies in different races, and the aim… read more here.
Keywords: molar teeth; apical constriction; incisors molars; incisor molar ... See more keywords
Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.60234
Abstract: Neural tube closure defects are a major cause of infant mortality, with exencephaly accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube closure are not well understood. Here, we show that… read more here.
Keywords: neural tube; tube closure; cranial neural; apical constriction ... See more keywords