Building an apical domain in the early mouse embryo: Lessons, challenges and perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2019.11.005
Abstract: Cell polarization is critical for lineage segregation and morphogenesis during mammalian embryogenesis. However, the processes and mechanisms that establish cell polarity in the mammalian embryo are not well understood. Recent studies suggest that unique regulatory… read more here.
Keywords: mouse embryo; cell; apical domain;
Microtubule motor transport in the delivery of melanosomes to the actin-rich, apical domain of in the retinal pigment epithelium.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.242214
Abstract: Melanosomes are motile, light-absorbing organelles, present in pigment cells of the skin and eye. It has been proposed that melanosome localization, in both skin melanocytes and the retinal pigment epithelium (RPE), involves melanosome capture from… read more here.
Keywords: microtubule; retinal pigment; melanosomes actin; apical domain ... See more keywords
Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00451
Abstract: Plasmodium parasites undergo a dramatic transformation during the liver stage of their life cycle, amplifying over 10,000-fold inside infected hepatocytes within a few days. Such a rapid growth requires large-scale interactions with, and manipulations of,… read more here.
Keywords: plasmodium; development; liver stage; apical domain ... See more keywords
Muscle Histopathological Abnormalities in a Patient With a CCT5 Mutation Predicted to Affect the Apical Domain of the Chaperonin Subunit
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.887336
Abstract: Recognition of diseases associated with mutations of the chaperone system genes, e.g., chaperonopathies, is on the rise. Hereditary and clinical aspects are established, but the impact of the mutation on the chaperone molecule and the… read more here.
Keywords: apical domain; muscle; subunit; cct5 ... See more keywords
Human embryo polarization requires PLC signaling to mediate trophectoderm specification
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65068
Abstract: Apico-basal polarization of cells within the embryo is critical for the segregation of distinct lineages during mammalian development. Polarized cells become the trophectoderm (TE), which forms the placenta, and apolar cells become the inner cell… read more here.
Keywords: embryo polarization; plc signaling; polarization; human embryo ... See more keywords