Articles with "apical membrane" as a keyword



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CD320 expression and apical membrane targeting in renal and intestinal epithelial cells.

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Published in 2022 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2021.12.158

Abstract: Vitamin B12 is an essential nutrient acquired via dietary intake. Receptor-mediated endocytosis is a key mechanism in vitamin B12 absorption, cellular uptake, and reabsorption. CD320 is a type I transmembrane protein responsible for cellular uptake… read more here.

Keywords: cd320; apical membrane; vitamin b12; membrane targeting ... See more keywords
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Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

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Published in 2017 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e16-07-0541

Abstract: The polarity regulator Par3 directs the reorganization of the apical membrane in polarized cells through the action of phosphatidylinositol 3-kinase and the Rac1 exchange factor Tiam1. This mechanism may be exploited by pathogens to bypass… read more here.

Keywords: par3 integrates; apical membrane; phosphatidylinositol kinase;
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The basolateral vesicle sorting machinery and basolateral proteins are recruited to the site of enteropathogenic E. coli microcolony growth at the apical membrane

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0179122

Abstract: Foodborne Enteropathogenic Escherichia coli (EPEC) infections of the small intestine cause diarrhea especially in children and are a major cause of childhood death in developing countries. EPEC infects the apical membrane of the epithelium of… read more here.

Keywords: apical membrane; basolateral proteins; microcolony growth; microcolony ... See more keywords
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Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding study

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0183198

Abstract: Malaria, a disease endemic in many tropical and subtropical regions, is caused by infection of the erythrocyte by the apicomplexan parasite Plasmodium. Host-cell invasion is a complex process but two Plasmodium proteins, Apical Membrane Antigen… read more here.

Keywords: protein; apical membrane; vivax; reactivity ... See more keywords
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Na+/HCO3- Cotransporter NBCn2 Mediates HCO3- Reclamation in the Apical Membrane of Renal Proximal Tubules.

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Published in 2017 at "Journal of the American Society of Nephrology : JASN"

DOI: 10.1681/asn.2016080930

Abstract: The kidney maintains systemic acid-base balance by reclaiming from the renal tubule lumen virtually all HCO3- filtered in glomeruli and by secreting additional H+ to titrate luminal buffers. For proximal tubules, which are responsible for… read more here.

Keywords: apical membrane; hco3 reclamation; proximal tubules; nbcn2 ... See more keywords
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Immunization of Cattle With Recombinant Structural Ectodomains I and II of Babesia bovis Apical Membrane Antigen 1 [BbAMA-1(I/II)] Induces Strong Th1 Immune Response

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Published in 2022 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2022.917389

Abstract: Both strong innate and adaptive immune responses are an important component of protection against intraerythrocytic protozoan parasites. Resistance to bovine babesiosis is associated with interferon (IFN)-γ mediated responses. CD4+ T cells and macrophages have been… read more here.

Keywords: bbama; apical membrane; membrane antigen; immune response ... See more keywords
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Recombinant Vaccinia Virus Expressing Plasmodium berghei Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against P. berghei Infection in Mice

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Published in 2022 at "Tropical Medicine and Infectious Disease"

DOI: 10.3390/tropicalmed7110350

Abstract: Recombinant vaccinia viruses (rVV) are effective antigen delivery vectors and are researched widely as vaccine platforms against numerous diseases. Apical membrane antigen 1 (AMA1) is one of the candidate antigens for malaria vaccines but rising… read more here.

Keywords: recombinant vaccinia; apical membrane; berghei; membrane antigen ... See more keywords