Parameter‐Tuned Pulsed Wave Photobiomodulation Enhances Stem Cells From Apical Papilla Differentiation: Evidence From Gene and Protein Analyses
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202400348
Abstract: This study examines the effects of pulsed wave photobiomodulation (pwPBM) on the osteogenic differentiation of stem cells from the apical papilla (SCAP). Using 810 nm near‐infrared (NIR) light with 300 Hz pulses and a 30% duty cycle,… read more here.
Keywords: cells apical; wave photobiomodulation; pulsed wave; stem cells ... See more keywords
Unveiling diversity of stem cells in dental pulp and apical papilla using mouse genetic models: a literature review
Sign Up to like & getrecommendations! Published in 2020 at "Cell and Tissue Research"
DOI: 10.1007/s00441-020-03271-0
Abstract: The dental pulp, a non-mineralized connective tissue uniquely encased within the cavity of the tooth, provides a niche for diverse arrays of dental mesenchymal stem cells. Stem cells in the dental pulp, including dental pulp… read more here.
Keywords: cells dental; stem cells; apical papilla; dental pulp ... See more keywords
Erythropoietin (rhEPOa) promotes endothelial transdifferentiation of stem cells of the apical papilla (SCAP).
Sign Up to like & getrecommendations! Published in 2018 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.09.001
Abstract: OBJECTIVE Mesenchymal stem cells (MSCs) have attracted worldwide attention for their capacity to repair damaged tissue, immunosuppression, ability to differentiate into several cell types and their secretome. Earlier studies have demonstrated their angiogenic potential in… read more here.
Keywords: endothelial transdifferentiation; apical papilla; scap; stem cells ... See more keywords
A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dental sciences"
DOI: 10.1016/j.jds.2021.01.012
Abstract: Background/purpose CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum. But the comprehensive role of CD24 in… read more here.
Keywords: cells apical; stem cells; cd24; cd24 scaps ... See more keywords
Effect of bFGF on the growth and matrix turnover of stem cells from human apical papilla: Role of MEK/ERK signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.12.013
Abstract: BACKGROUND/PURPOSE Basic fibroblast growth factor (bFGF) exhibits multiple biological functions in various tissues. Stem cells from apical papilla (SCAP) can be isolated from human apical papilla tissues in developmental teeth of children. The purposes of… read more here.
Keywords: mek erk; apical papilla; bfgf; scap ... See more keywords
The Effects of Irrigants on the Survival of Human Stem Cells of the Apical Papilla, Including Endocyn
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2017.09.001
Abstract: Introduction: Endocyn, a pH‐neutral solution of hypochlorous acid and hypochlorite has been developed for use as an endodontic irrigant. The purpose of this study was to evaluate the effect of Endocyn on human periodontal ligament… read more here.
Keywords: cells apical; stem cells; apical papilla; alkaline phosphatase ... See more keywords
Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells
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DOI: 10.1038/s41598-019-50367-x
Abstract: After spinal cord injury (SCI) chronic inflammation hampers regeneration. Influencing the local microenvironment after SCI may provide a strategy to modulate inflammation and the immune response. The objectives of this work were to determine whether… read more here.
Keywords: inflammation microglial; apical papilla; inflammation; microglial cells ... See more keywords
PD-1 suppresses the osteogenic and odontogenic differentiation of stem cells from dental apical papilla via targeting SHP2/NF-κB axis.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac037
Abstract: Stem cells from the apical papilla (SCAPs) are important for tooth root development and regeneration of root dentin. Here, we examined the expression of programmed cell death protein-1 (PD-1) in SCAPs and investigated the effect… read more here.
Keywords: differentiation; odontogenic differentiation; apical papilla; stem cells ... See more keywords
Analysis of gene expression profiles between apical papilla tissues, stem cells from apical papilla and cell sheet to identify the key modulators in MSCs niche
Sign Up to like & getrecommendations! Published in 2017 at "Cell Proliferation"
DOI: 10.1111/cpr.12337
Abstract: The microenvironmental niche plays the key role for maintaining the cell functions. The stem cells from apical papilla (SCAPs) are important for tooth development and regeneration. However, there is limited knowledge about the key factors… read more here.
Keywords: expression profiles; papilla; apical papilla; gene expression ... See more keywords
Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton
Sign Up to like & getrecommendations! Published in 2025 at "International Endodontic Journal"
DOI: 10.1111/iej.14213
Abstract: Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic… read more here.
Keywords: differentiation; scap; stem cells; odontogenic differentiation ... See more keywords
Overexpression of ephrinB2 in stem cells from apical papilla accelerates angiogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.13042
Abstract: OBJECTIVES We aimed to accelerate angiogenesis in pulp regeneration by modulating ephrinB2 expression in stem cells from apical papilla (SCAPs). MATERIALS AND METHODS Stem cells from apical papilla were transducted with ephrinB2-lentiviral expression vector (ephrinB2-SCAPs)… read more here.
Keywords: gfp scaps; apical papilla; ephrinb2 scaps; cells apical ... See more keywords