Pharmacokinetics and Comparative Bioavailability of Apomorphine Sublingual Film and Subcutaneous Apomorphine Formulations in Patients with Parkinson’s Disease and “OFF” Episodes: Results of a Randomized, Three-Way Crossover, Open-Label Study
Sign Up to like & getrecommendations! Published in 2021 at "Neurology and Therapy"
DOI: 10.1007/s40120-021-00251-6
Abstract: In a pivotal study, apomorphine sublingual film (APL; KYNMOBI®) was an effective and generally well-tolerated on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD), approved across the dose range of 10–30 mg. Pharmacokinetics… read more here.
Keywords: bioavailability; apo apo; apomorphine formulations; open label ... See more keywords
Safety and efficacy of Melissa officinalis (lemon balm) on ApoA-I, Apo B, lipid ratio and ICAM-1 in type 2 diabetes patients: A randomized, double-blinded clinical trial.
Sign Up to like & getrecommendations! Published in 2018 at "Complementary therapies in medicine"
DOI: 10.1016/j.ctim.2018.07.015
Abstract: BACKGROUND The purpose of this study was to investigate the safety and effects of Melissa officinalis, a good source of bioactive components, on apolipoprotein (Apo)B, Apo A-I, and their ratio, lipids ratios and intercellular adhesion… read more here.
Keywords: apo apo; icam; type diabetes; apo ... See more keywords
Preparation of Apoastaxanthinals and Evaluation of Their Anti-inflammatory Action against Lipopolysaccharide-Stimulated Macrophages and Adipocytes
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DOI: 10.1021/acsomega.2c01164
Abstract: Apocarotenoids are carotenoid derivatives in which the polyene chain is cleaved via enzymatic or nonenzymatic action. They are found in animal tissues and carotenoid-containing foods. However, limited information on the biological functions of apocarotenoids is… read more here.
Keywords: inflammatory action; anti inflammatory; lipopolysaccharide stimulated; apo apo ... See more keywords
Rapid Changes in Serum Lipid Profiles during Combination Therapy with Daclatasvir and Asunaprevir in Patients Infected with Hepatitis C Virus Genotype 1b
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DOI: 10.5009/gnl17179
Abstract: Background/Aims Changes in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years. However, the clinical aspects of disturbed lipid metabolism in chronic HCV infection… read more here.
Keywords: changes serum; apo apo; lipid profiles; therapy ... See more keywords