Apolipoprotein A1 is associated with pulmonary vascular resistance and adverse clinical outcomes in patients with pulmonary hypertension secondary to heart failure
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DOI: 10.1002/pul2.12096
Abstract: Abstract Pulmonary hypertension secondary to heart failure (HF‐PH) combined with pulmonary vascular remodeling has a high mortality rate. Apolipoprotein A1 (ApoA1) has been shown to adversely affect outcomes in patients with HF. A prospective follow‐up… read more here.
Keywords: apoa1; pulmonary hypertension; apoa1 levels; pulmonary vascular ... See more keywords
Decreased serum apolipoprotein A1 level predicts poor prognosis of patients with de novo myelodysplastic syndromes
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DOI: 10.1186/s12885-022-09248-2
Abstract: Background Myelodysplastic syndromes (MDS) is a group of heterogeneous myeloid clonal diseases originating from hematopoietic stem cells. It has been demonstrated that apolipoproteins A1(ApoA1) are associated with disease risk in many cancer types. However, there… read more here.
Keywords: mds patients; level; low apoa1; myelodysplastic syndromes ... See more keywords
Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis
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DOI: 10.1186/s12944-020-01309-4
Abstract: Moderate alcohol intake in human increases HDL-cholesterol, and has protective effects against cardiovascular disease (CVD). Although de novo lipid synthesis inhibitors are highly effective in lowering total and LDL-cholesterol they have only modest effects on… read more here.
Keywords: cholesterol; apoa1; ethanol; upregulation apoa1 ... See more keywords
APOA1 Level is Negatively Correlated with the Severity of COVID-19
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DOI: 10.2147/ijgm.s332956
Abstract: Objective We used public data to analyze the proteomics, metabolomics and transcriptomics characteristics of COVID-19 patients to identify potential therapeutic targets. More importantly, we also collected clinical data for verification to make the analysis results… read more here.
Keywords: apoa1; covid patients; correlated severity; level ... See more keywords
Significant Implications of APOA1 Gene Sequence Variations and Its Protein Expression in Bladder Cancer
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DOI: 10.3390/biomedicines9080938
Abstract: Apolipoprotein A1 (APOA1) is a potential biomarker because of its variable concentration in different types of cancers. The current study is the first of its kind to evaluate the association between the APOA1 genotypes of… read more here.
Keywords: protein expression; bladder; expression; apoa1 ... See more keywords