Heterogeneity of Apolipoprotein B Levels Among Hispanic or Latino Individuals Residing in the US.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2024.4789
Abstract: Importance Apolipoprotein B (apoB) distribution and its implications as an atherosclerotic cardiovascular disease (ASCVD) risk-enhancing factor among individuals of diverse Hispanic or Latino backgrounds have not been described. Objective To describe the distribution of apoB… read more here.
Keywords: apob; ascvd risk; hispanic latino; latino ... See more keywords
A systematic review of LDLR, PCSK9, and APOB variants in Asia.
Sign Up to like & getrecommendations! Published in 2020 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2020.05.004
Abstract: BACKGROUND AND AIMS Genetic identification is a public health care concern for management of familial hypercholesterolemia (FH) associated cardiovascular morbidity and mortality. This study presents the spectrum and distribution of LDLR, APOB, PCSK9 gene mutations… read more here.
Keywords: apob; systematic review; review ldlr; pcsk9 ... See more keywords
The first Japanese cases of familial hypercholesterolemia due to a known pathogenic APOB gene variant, c.10580 G>A: p.(Arg3527Gln).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2020.05.007
Abstract: BACKGROUND We previously showed that patients without pathogenic variants in the LDLR and PCSK9 genes comprised approximately 40% of familial hypercholesterolemia (FH) cases. OBJECTIVE Our aim was to identify novel causative variants in Japanese patients… read more here.
Keywords: apob; pathogenic variants; apob gene; japanese cases ... See more keywords
Increased serum concentration of apolipoprotein B is associated with an increased risk of reaching renal replacement therapy in patients with diabetic kidney disease
Sign Up to like & getrecommendations! Published in 2020 at "Renal Failure"
DOI: 10.1080/0886022x.2020.1745235
Abstract: Abstract Objective Few studies have investigated the association of apolipoprotein B (ApoB) with the progression of diabetic kidney disease (DKD) and the risk of renal replacement therapy (RRT). Method In this retrospective cohort study, a… read more here.
Keywords: risk; apob; diabetic kidney; rrt ... See more keywords
Enzyme-Linked Immunoassay-Based Quantitative Measurement of Apolipoprotein B (ApoB) in Dried Blood Spots, a Biomarker of Cardiovascular Disease Risk
Sign Up to like & getrecommendations! Published in 2017 at "Biodemography and Social Biology"
DOI: 10.1080/19485565.2017.1283582
Abstract: ABSTRACT Apolipoprotein B (ApoB) is a strong predictor of cardiovascular disease, which remains the leading cause of mortality in both higher and lower income countries. Here, we adapted an enzyme-linked immunosorbent assay (ELISA) development kit… read more here.
Keywords: apob; blood spots; dried blood; apolipoprotein apob ... See more keywords
A Translational Tool to Facilitate Use of Apolipoprotein B for Clinical Decision-Making.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac161
Abstract: BACKGROUND Despite recent large-scale discordance studies showing definitively that atherosclerotic cardiovascular disease (ASCVD) risk correlates better with apolipoprotein B (apoB) than with low-density lipoprotein cholesterol (LDL-C), the latter remains the recommended metric for guiding lipid-lowering… read more here.
Keywords: translational tool; apob; facilitate use; ascvd risk ... See more keywords
Interplay of Atherogenic Particle Number and Particle Size and the Risk of Coronary Heart Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac172
Abstract: BACKGROUND We examined the interplay of apolipoprotein B (apoB) and LDL particle size, approximated by the LDL-cholesterol (LDL-C)/apoB ratio, on the risk of new-onset coronary heart disease (CHD). METHODS Participants without cardiovascular disease from the… read more here.
Keywords: disease; apob; risk; heart ... See more keywords
Reducing the Damage of Ox-LDL/LOX-1 Pathway to Vascular Endothelial Barrier Can Inhibit Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7541411
Abstract: Aim The destruction of the vascular endothelial barrier mediated by Ox-LDL is the initial link to atherosclerosis. Here, we aimed to determine whether the immunological intervention with Ox-ApoB polypeptide fragment (Ox-ApoB-PF) can block the deposition… read more here.
Keywords: endothelial barrier; endothelial cells; apob; atherosclerosis ... See more keywords
Abstract 4368444: Triglyceride in different ApoB-containing lipoproteins and risk of coronary artery disease: particle type matters
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4368444
Abstract: Introduction: Plasma triglyceride (TG), mostly embedded in apoB-containing particle (apoB-P), has been proposed as a potential residual risk factor for atherosclerotic cardiovascular disease (ASCVD). However, the atherogenicity of TG in different types of ApoB-P, especially… read more here.
Keywords: disease; different apob; risk; apob ... See more keywords
Abstract 4369053: Coronary Artery Calcium Score Modifies the Risk of Coronary Heart Disease Associated with Apolipoprotein B
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4369053
Abstract: Introduction: Apolipoprotein B (ApoB) and coronary artery calcium score (CAC) are well-established risk factors for coronary heart disease (CHD). However, the interaction between these risk factors on CHD risk has not been well-studied. We investigated… read more here.
Keywords: group cac; high apob; apob group; group ... See more keywords
FVIII-associated LDL circulates longer and participates in blood clot formation
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-17
Abstract: Background and rationale. Hemophilia A is a bleeding disorder caused by deficient or absent in coagulation factor VIII (FVIII). Several clinical studies reported overall lower prevalence of atherosclerotic cardiovascular diseases in hemophilia patients, but the… read more here.
Keywords: cholesterol; ldl; fviii deficient; apob ... See more keywords