N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels
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DOI: 10.1093/eurheartj/ehz209
Abstract: Abstract Aims Elevated apolipoprotein C-III (apoC-III) levels are associated with hypertriglyceridaemia and coronary heart disease. AKCEA-APOCIII-LRx is an N-acetyl galactosamine-conjugated antisense oligonucleotide targeted to the liver that selectively inhibits apoC-III protein synthesis. Methods and results… read more here.
Keywords: akcea apociii; galactosamine conjugated; acetyl galactosamine; apociii lrx ... See more keywords