An in vitro mechanistic approach towards understanding the distinct pathways regulating insulin resistance and adipogenesis by apocynin
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biosciences"
DOI: 10.1007/s12038-020-00134-2
Abstract: Adipogenesis is a cascade of processes that entail the differentiation of fibroblasts into mature adipocytes, which results in the accumulation of triglycerides in the adipose cells due to high dietary supplements. This physiological condition increases… read more here.
Keywords: adipogenesis apocynin; adipogenesis; apocynin; insulin signaling ... See more keywords
Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105821
Abstract: Mounting evidence has demonstrated that acute pancreatitis (AP) is one of the causes of multiple organ damage. NADPH (nicotinamide adenine dinucleotide phosphate) act as a substrate of NADPH oxidase (NOX) to generate reactive oxygen species… read more here.
Keywords: acute pancreatitis; apocynin; lung injury; suppressing nlrp3 ... See more keywords
Influence of Dimerization of Apocynin on Its Effects in Experimental Colitis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b00872
Abstract: Apocynin has been widely used as an inhibitor of the nicotinamide adenine dinucleotide phosphate oxidase (NADPH-oxidase) system and shows promise as an anti-inflammatory drug. Diapocynin, the dimeric product generated by the oxidation of apocynin in… read more here.
Keywords: anti inflammatory; influence dimerization; dimerization apocynin; colitis ... See more keywords
Apocynin derivatives from Iris tectorum
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2016.1268128
Abstract: Abstract Phytochemical investigation of the rhizomes of Iris tectorum resulted in the isolation and characterization of three new apocynin derivatives, apocynin-4-O-β-D-(6′-O-syringyl)glucopyranoside (1), scrophenoside C-7-ethyl ether (2, 3), together with a new naturally occurring compound but… read more here.
Keywords: derivatives iris; apocynin derivatives; apocynin; iris tectorum ... See more keywords
Inhibition of oxidative stress by apocynin attenuated COPD progression and vascular injury by cigarette smoke exposure.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of pharmacology"
DOI: 10.1111/bph.16068
Abstract: BACKGROUND AND PURPOSE Cardiovascular disease (CVD) affects up to half of the patients with chronic obstructive pulmonary disease (COPD), and exerts deleterious impact on health outcomes and survivability. Vascular endothelial dysfunction marks the onset of… read more here.
Keywords: cigarette smoke; copd progression; apocynin; oxidative stress ... See more keywords
Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/9258937
Abstract: Environmental chronic stress (ECS) has been identified as a trigger of acute coronary syndromes (ACS). Changes in redox balance, enhanced reactive oxygen species (ROS) production, and platelet hyperreactivity were detected in both ECS and ACS.… read more here.
Keywords: chronic stress; megakaryopoiesis; stress; apocynin ... See more keywords