DNA methylation of TOMM40-APOE-APOC2 in Alzheimer’s disease
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DOI: 10.1038/s10038-017-0393-8
Abstract: The apolipoprotein E (APOE) ε4 allele is the major genetic risk factor for Alzheimer’s disease (AD). Multiple regulatory elements, spanning the extended TOMM40-APOE-APOC2 region, regulate gene expression at this locus. Regulatory element DNA methylation changes… read more here.
Keywords: apoe apoc2; methylation; tomm40 apoe; region ... See more keywords