Articles with "apoe gene" as a keyword



Effect of apolipoprotein E (APOE) gene polymorphisms on the lipid profile of children being treated for acute lymphoblastic leukemia

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Published in 2024 at "International Journal of Hematology"

DOI: 10.1007/s12185-024-03748-6

Abstract: Medications used to treat acute lymphoblastic leukemia (ALL), such as l-asparaginase, can cause blood lipid disturbances. These can also be associated with polymorphisms of the lipoprotein lipase (LpL) and apolipoprotein E (APOE) genes. We aimed… read more here.

Keywords: lipid profile; acute lymphoblastic; lymphoblastic leukemia; apolipoprotein apoe ... See more keywords

APOE gene polymorphism alters cerebral oxygen saturation and quantitative EEG in early-stage traumatic brain injury

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Published in 2022 at "Clinical Neurophysiology"

DOI: 10.1016/j.clinph.2022.01.131

Abstract: OBJECTIVE To investigate the influence of apolipoprotein E (APOE) gene polymorphism on regional cerebral oxygen saturation (rScO2) and quantitative electroencephalogram (QEEG) at the early phase of adult traumatic brain injury (TBI). METHODS clinical data of… read more here.

Keywords: apoe gene; tbi; gene polymorphism; early stage ... See more keywords

The hypoperfusion intensity ratio associates with APOE gene polymorphism in acute ischemic stroke patients with large vessel occlusion

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-16237-5

Abstract: Determine whether APOE gene polymorphism is associated with hypoperfusion intensity ratio (HIR) in acute ischemic stroke (AIS) patients with large vessel occlusion (LVO). Continuously reviewed hospitalized LVO-AIS patients. According to whether the patients carried APOE… read more here.

Keywords: stroke; gene polymorphism; intensity ratio; hypoperfusion intensity ... See more keywords

“Association of APOE gene polymorphisms with primary open angle glaucoma in Brazilian patients”

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Published in 2020 at "Ophthalmic Genetics"

DOI: 10.1080/13816810.2020.1849314

Abstract: ABSTRACT Background: Primary open-angle glaucoma (POAG) is a multifactorial disease that affects 65.5 million people worldwide. In addition to the genetic variants already established as indicators of greater risk for POAG, the apolipoprotein (APOE) gene… read more here.

Keywords: apoe gene; risk; association; glaucoma ... See more keywords

Lipoprotein glomerulopathy resulting from compound heterogeneous mutations of APOE gene

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000028718

Abstract: Abstract Rationale: Lipoprotein glomerulopathy (LPG) is a rare glomerular disease characterized by the deposition of lipoprotein thrombi in glomerular capillaries. The disease is characterized by proteinuria, progressive renal failure, and characteristic lipoprotein thrombosis in glomerular… read more here.

Keywords: compound heterogeneous; mutations apoe; apoe gene; gene ... See more keywords

APOE and familial hypercholesterolemia

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Published in 2024 at "Current Opinion in Lipidology"

DOI: 10.1097/mol.0000000000000937

Abstract: Purpose of review Autosomal dominant hypercholesterolemia is a common cause of cardiovascular disease. In addition to the classic genes that cause hypercholesterolemia, LDLR, APOB and PCSK9, a new locus has emerged as a candidate to… read more here.

Keywords: hypercholesterolemia; leu167del; familial hypercholesterolemia; mutation ... See more keywords

Meta-Analysis of the Relationship between the APOE Gene and the Onset of Parkinson's Disease Dementia

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Published in 2018 at "Parkinson's Disease"

DOI: 10.1155/2018/9497147

Abstract: Purpose To clarify the relationship between certain genotypes or alleles of the APOE gene and the onset risk of Parkinson's disease dementia (PDD). Methods The PubMed, Cochrane, Embase, CBM, CNKI, and Wanfang databases were searched… read more here.

Keywords: apoe gene; risk; meta analysis; parkinson disease ... See more keywords