Effect of Apolipoprotein E Genotypes on Huntington’s Disease Phenotypes in a Han Chinese Population
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DOI: 10.1007/s12264-019-00360-1
Abstract: Huntington’s disease (HD) is an autosomal dominant degenerative disease that mainly encompasses movement, cognition, and behavioral symptoms. The apolipoprotein E (APOE) gene is thought to be associated with many neurodegenerative diseases. Here, we enrolled a… read more here.
Keywords: apoe genotypes; phenotypes han; huntington disease; disease ... See more keywords
Association of ApoE Genotypes and Recovery From Intracerebral Hemorrhage in Very Low Birth Weight Infants
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DOI: 10.1161/strokeaha.120.033432
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Associations of APOE genotypes with intracerebral hemorrhage (ICH) in preterm infants were previously described. In adults, APOE-ε4 genotype has been proposed as susceptibility factor… read more here.
Keywords: apoe genotype; apoe genotypes; low birth; apoe ... See more keywords
Relationships of APOE Genotypes With Small RNA and Protein Cargo of Brain Tissue Extracellular Vesicles From Patients With Late-Stage AD
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DOI: 10.1212/nxg.0000000000200026
Abstract: Background and Objectives Variants of the apolipoprotein E (APOE) gene are the greatest known risk factors for sporadic Alzheimer disease (AD). Three major APOE isoform alleles, ε2, ε3, and ε4, encode and produce proteins that… read more here.
Keywords: apoe genotypes; extracellular vesicles; late stage; rna protein ... See more keywords
Metabolite Profile of Alzheimer’s Disease in the Frontal Cortex as Analyzed by HRMAS 1H NMR
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DOI: 10.3389/fnagi.2018.00424
Abstract: Background: Investigation on neurochemical changes in the frontal cortex in individuals with Alzheimer’s disease (AD) and different Apolipoprotein E (APOE) genotypes, using ex vivo solid-state high-resolution NMR analysis, may lead to a better understanding of… read more here.
Keywords: apoe genotypes; cortex; alzheimer disease; frontal cortex ... See more keywords
APOE Genotypes Modulate Inflammation Independently of Their Effect on Lipid Metabolism
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DOI: 10.3390/ijms232112947
Abstract: The association between APOE genotypes and cardiovascular disease (CVD) is partially mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and other cardiovascular risk factors. Data from the Aragon Workers Health Study (AWHS)… read more here.
Keywords: apoe genotypes; apoe4 carriers; ldl particles; crp levels ... See more keywords