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Published in 2019 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-019-00360-1
Abstract: Huntington’s disease (HD) is an autosomal dominant degenerative disease that mainly encompasses movement, cognition, and behavioral symptoms. The apolipoprotein E (APOE) gene is thought to be associated with many neurodegenerative diseases. Here, we enrolled a…
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Keywords:
apoe genotypes;
phenotypes han;
huntington disease;
disease ... See more keywords
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Published in 2021 at "Stroke"
DOI: 10.1161/strokeaha.120.033432
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Associations of APOE genotypes with intracerebral hemorrhage (ICH) in preterm infants were previously described. In adults, APOE-ε4 genotype has been proposed as susceptibility factor…
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Keywords:
apoe genotype;
apoe genotypes;
low birth;
apoe ... See more keywords
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2
Published in 2022 at "Neurology: Genetics"
DOI: 10.1212/nxg.0000000000200026
Abstract: Background and Objectives Variants of the apolipoprotein E (APOE) gene are the greatest known risk factors for sporadic Alzheimer disease (AD). Three major APOE isoform alleles, ε2, ε3, and ε4, encode and produce proteins that…
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Keywords:
apoe genotypes;
extracellular vesicles;
late stage;
rna protein ... See more keywords
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1
Published in 2019 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2018.00424
Abstract: Background: Investigation on neurochemical changes in the frontal cortex in individuals with Alzheimer’s disease (AD) and different Apolipoprotein E (APOE) genotypes, using ex vivo solid-state high-resolution NMR analysis, may lead to a better understanding of…
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Keywords:
apoe genotypes;
cortex;
alzheimer disease;
frontal cortex ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112947
Abstract: The association between APOE genotypes and cardiovascular disease (CVD) is partially mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and other cardiovascular risk factors. Data from the Aragon Workers Health Study (AWHS)…
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Keywords:
apoe genotypes;
apoe4 carriers;
ldl particles;
crp levels ... See more keywords