Phosphatidylglucose Alleviates Atherosclerosis by Increasing Cholesterol Alienation to Bile Acids and Cholesterol Efflux in ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12626
Abstract: BACKGROUND Phosphatidylcholine (PC) are considered to be the major dietary sources for choline, which is associated with the atherosclerosis progress. Thus, phosphatidylglucose (PG) was prepared by enzymatic modification of PC to study the effects on… read more here.
Keywords: cholesterol alienation; increasing cholesterol; bile acids; cholesterol ... See more keywords
Anti-atherosclerotic effects of Lactobacillus plantarum ATCC 14917 in ApoE−/− mice through modulation of proinflammatory cytokines and oxidative stress
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10693-x
Abstract: Atherosclerosis is a chronic inflammatory disease mediated by monocyte infiltration and cholesterol deposition into the subendothelial area, resulting in foam cell development. Probiotics are live bacteria that are beneficial for health when administered orally in… read more here.
Keywords: lactobacillus plantarum; plantarum atcc; atcc 14917; apoe mice ... See more keywords
Effect of Quercetin on Atherosclerosis Based on Expressions of ABCA1, LXR-α and PCSK9 in ApoE-/- Mice
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-019-2942-9
Abstract: ObjectiveTo investigate the effect of quercetin on ATP binding cassette transporter A1 (ABCA1), liver X receptor (LXR), and proprotein convertase subtilisin/kexin type 9 (PCSK9) expressions in apoE-knockout (ApoE-/-) mice.MethodsThe high-fat diet-induced atherosclerosis (AS) in ApoE-/-… read more here.
Keywords: lxr pcsk9; group; mice; apoe mice ... See more keywords
Aneurysm severity is suppressed by deletion of CCN4
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-021-00623-5
Abstract: Patients with abdominal aortic aneurysms are frequently treated with high-risk surgery. A pharmaceutical treatment to reverse aneurysm progression could prevent the need for surgery and save both lives and healthcare resources. Since CCN4 regulates cell… read more here.
Keywords: ccn4; ccn4 apoe; deletion ccn4; apoe mice ... See more keywords
Nicotinic acetylcholine receptor alpha 7 stimulation dampens splenic myelopoiesis and inhibits atherogenesis in Apoe-/- mice.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.08.010
Abstract: BACKGROUND AND AIMS Monocyte levels predict cardiovascular outcomes and play a causal role in atherogenesis. Monocytes can be produced in the spleen and track to the atherosclerotic lesion in significant numbers. The cholinergic system has… read more here.
Keywords: splenic myelopoiesis; stimulation; receptor alpha; nicotinic acetylcholine ... See more keywords
Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.226
Abstract: Atherosclerosis is characterized by chronic low-grade inflammation, large numbers of activated leukocytes, and the deposition of cholesterol and lipids in the artery wall. This project has investigated a novel seleno-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) as a potential… read more here.
Keywords: effects novel; novel selenosugar; apoe mice; aortic rings ... See more keywords
Expression of miRNA‐155 in carotid atherosclerotic plaques of apolipoprotein E knockout (ApoE−/−) mice and the interventional effect of rapamycin
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.02.026
Abstract: Abstract Carotid atherosclerosis (AS) is an inflammatory process and is the primary pathogenesis of cerebrovascular disease. Many factors are responsible for development of atherosclerosis such as inflammation and autophagy. It is reported that microRNAs (miRNAs)… read more here.
Keywords: expression; autophagy; apoe mice; mirna 155 ... See more keywords
Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.12.031
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Semen celosiae is a traditional Chinese medicine for purging hepatic pathogenic fire and removing nebula to improve eyesight, treating hepatopyretic vertigo and hypertension. It possesses a serial of potential bioactivities such as hepatoprotection,… read more here.
Keywords: mrna expression; autophagy; apoe mice; celosins inhibit ... See more keywords
Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.07.046
Abstract: Abstract Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol levels. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause of death worldwide. The present study was… read more here.
Keywords: saponins sea; cholesterol; apoe mice; atherosclerosis ... See more keywords
Bowman-Birk Major Type Trypsin Inhibitor Derived from Foxtail Millet Bran Attenuate Atherosclerosis via Remodeling Gut Microbiota in ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c05747
Abstract: Foxtail millet proteins and their hydrolysates have the potential to prevent atherosclerosis (AS). In our present study, a novel Bowman-Birk type major trypsin inhibitor from foxtail millet bran (FMB-BBTI) with an anti-AS effect was obtained… read more here.
Keywords: fmb bbti; millet bran; foxtail millet; apoe mice ... See more keywords
Antiatherosclerotic effect of dehydrocorydaline on ApoE-/- mice: inhibition of macrophage inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00769-3
Abstract: Despite improvements in cardiovascular disease (CVD) outcomes by cholesterol-lowering statin therapy, the high rate of CVD is still a great concern worldwide. Dehydrocorydaline (DHC) is an alkaloidal compound isolated from the traditional Chinese herb Corydalis… read more here.
Keywords: dhc; inflammation; macrophage; apoe mice ... See more keywords