Prediction of clinical diagnosis of Alzheimer’s disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0764-y
Abstract: The strongest genetic risk factor for Alzheimer’s disease (AD) is the ε4 allele of Apolipoprotein E (APOE) and recent genome-wide association meta-analyses have confirmed additional associated genetic loci with smaller effects. The aim of this… read more here.
Keywords: cause dementia; apoe status; based cohort; cause ... See more keywords
APOE genetics influence murine gut microbiome
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DOI: 10.1038/s41598-022-05763-1
Abstract: Apolipoprotein E ( APOE ) alleles impact pathogenesis and risk for multiple human diseases, making them primary targets for disease treatment and prevention. Previously, we and others reported an association between APOE alleles and the… read more here.
Keywords: mice; gut microbiome; apoe; apoe status ... See more keywords
Air Pollution and Risk of Neurobehavioral Problems: Is APOE ε4 Status a Factor?
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DOI: 10.1289/ehp4810
Abstract: Photograph of elementary-age children exiting a school bus read more here.
Keywords: air pollution; apoe status; neurobehavioral problems; problems apoe ... See more keywords