APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid
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DOI: 10.1126/scitranslmed.aay1809
Abstract: APOE4 exacerbates α-synuclein pathology in a synucleinopathy mouse model, and APOE4 genotype associates with increased α-synuclein pathology in humans. APOE4 beyond amyloid Although several genetic risk factors for neurodegenerative disorders have been identified, often the… read more here.
Keywords: synuclein pathology; apoe4 exacerbates; mouse; pathology ... See more keywords