APOL1 Renal-Risk Variants Induce Mitochondrial Dysfunction.
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DOI: 10.1681/asn.2016050567
Abstract: APOL1 G1 and G2 variants facilitate kidney disease in blacks. To elucidate the pathways whereby these variants contribute to disease pathogenesis, we established HEK293 cell lines stably expressing doxycycline-inducible (Tet-on) reference APOL1 G0 or the… read more here.
Keywords: renal risk; apol1 renal; risk variants; mitochondrial dysfunction ... See more keywords