Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-018-0653-x
Abstract: Low-carbohydrate diets are considered to be an effective approach to weight loss and have, subsequently, grown in popularity. Despite the apparent health benefits that these diets may provide for insulin resistance, hypertension, and dyslipidemia, their… read more here.
Keywords: carbohydrate high; apolipoprotein deficient; high fat; low carbohydrate ... See more keywords
Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.04.229
Abstract: BACKGROUND AND AIMS Local macrophage proliferation is linked to enhanced atherosclerosis progression. Our previous study found that troglitazone, a thiazolidinedione (TZD), suppressed oxidized low-density lipoprotein (Ox-LDL)-induced macrophage proliferation. However, its effects and mechanisms are unclear.… read more here.
Keywords: mice; macrophage proliferation; pioglitazone; proliferation ... See more keywords
GW29-e1791 Nicotine promotes atherosclerosis development in apolipoprotein E-deficient mice through alpha 1 nicotinic acetylcholine receptor on RAW264.7 and MOVAS cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.217
Abstract: In our study, we investigated whether nicotine promotes the development of atherosclerosis throughout alpha 1 nicotinic acetylcholine receptor in apolipoprotein E-deficient mice .In vitro, we investigated whether the migration and proliferation of VSMC and macrophage… read more here.
Keywords: alpha nicotinic; nicotinic acetylcholine; apolipoprotein deficient; nicotine promotes ... See more keywords
Interleukin-17A influences the vulnerability rather than the size of established atherosclerotic plaques in apolipoprotein E-deficient mice
Sign Up to like & getrecommendations! Published in 2022 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0072
Abstract: Abstract Interleukin (IL)-17A plays a role in the development of atherosclerotic plaques; however, the mechanism remains unclear. In this study, apolipoprotein E-deficient (ApoE–/–) mice were fed a high-fat diet to induce atherosclerosis, followed by the… read more here.
Keywords: vulnerability; established atherosclerotic; apolipoprotein deficient; size established ... See more keywords
Atheroregressive Potential of the Treatment with a Chimeric Monoclonal Antibody against Sulfated Glycosaminoglycans on Pre-existing Lesions in Apolipoprotein E-Deficient Mice
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00782
Abstract: The retention of lipoprotein particles in the intima, in particular to glycosaminoglycan side chains of proteoglycans, is a critical step in atherosclerosis initiation. Administration of chP3R99, a chimeric mouse/human monoclonal antibody inducing an anti-idiotypic network… read more here.
Keywords: treatment; antibody; apolipoprotein deficient; mice ... See more keywords
Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081117
Abstract: Background: The aim of the study was to define whether edaravone, a free-radical scavenger, influenced angiotensin II (AngII)-induced atherosclerosis and abdominal aortic aneurysms (AAAs) formation. Methods: Male apolipoprotein E-deficient mice (8–12 weeks old) were fed… read more here.
Keywords: apolipoprotein deficient; deficient mice; angii induced; mice ... See more keywords
Comparison of Selenium Nanoparticles and Sodium Selenite on the Alleviation of Early Atherosclerosis by Inhibiting Endothelial Dysfunction and Inflammation in Apolipoprotein E-Deficient Mice
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111612
Abstract: Atherosclerosis and related cardiovascular diseases represent the greatest threats to human health, worldwide. Previous animal studies showed that selenium nanoparticles (SeNPs) and Na2SeO3 might have anti-atherosclerotic activity, but the underlying mechanisms are poorly elucidated. This… read more here.
Keywords: senps na2seo3; apolipoprotein deficient; endothelial dysfunction; atherosclerosis ... See more keywords
Yirui Capsules Alleviate Atherosclerosis by Improving the Lipid Profile and Reducing Inflammation in Apolipoprotein E-Deficient Mice
Sign Up to like & getrecommendations! Published in 2018 at "Nutrients"
DOI: 10.3390/nu10020142
Abstract: Atherosclerosis (AS) is the main cause of cardiovascular diseases. This study investigated Yirui (YR) capsules, whose ingredients are available in health food stores, against AS and the underlying mechanisms. Male apolipoprotein E-deficient mice fed a… read more here.
Keywords: lipid profile; apolipoprotein deficient; yirui capsules; deficient mice ... See more keywords
Betaine Supplementation Attenuates S-Adenosylhomocysteine Hydrolase-Deficiency-Accelerated Atherosclerosis in Apolipoprotein E-Deficient Mice
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030718
Abstract: S-adenosylhomocysteine (SAH) is a risk factor of cardiovascular diseases and atherosclerosis. However, the causal association between SAH and atherosclerosis is still uncertain. In the present study, heterozygous SAH hydrolase (SAHH+/−) knockout mice were bred with… read more here.
Keywords: apolipoprotein deficient; betaine supplementation; atherosclerosis; mice ... See more keywords
Extract of Curcuma zedoaria R. prevents atherosclerosis in apolipoprotein E-deficient mice
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition Research and Practice"
DOI: 10.4162/nrp.2021.15.3.319
Abstract: BACKGROUND/OBJECTIVES Curcuma zedoaria R. (Zingiberaceae) has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a C. zedoaria extract (CzE) affected… read more here.
Keywords: curcuma zedoaria; apolipoprotein deficient; mice; extract ... See more keywords