Apolipoprotein E mimetic peptide, CN‐105, improves outcomes in ischemic stroke
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.399
Abstract: At present, the absence of a pharmacological neuroprotectant represents an important unmet clinical need in the treatment of ischemic and traumatic brain injury. Recent evidence suggests that administration of apolipoprotein E mimetic therapies represent a… read more here.
Keywords: apolipoprotein mimetic; ischemic stroke; peptide 105; mimetic peptide ... See more keywords
Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.11.027
Abstract: Disruption of endothelial monolayer integrity is the primary instigating factor for many cardiovascular diseases. High density lipoprotein (HDL) oxidized by heme enzyme myeloperoxidase (MPO) is dysfunctional in promoting endothelial repair. Apolipoprotein A-1 mimetic 4F with… read more here.
Keywords: apolipoprotein mimetic; oxidized hdl; hdl; migration ... See more keywords
Long-Term Liver Expression of an Apolipoprotein A-I Mimetic Peptide Attenuates Interferon-Alpha-Induced Inflammation and Promotes Antiviral Activity
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.620283
Abstract: Apolipoprotein A-I mimetic peptides are amphipathic alpha-helix peptides that display similar functions to apolipoprotein A-I. Preclinical and clinical studies have demonstrated the safety and efficacy of apolipoprotein A-I mimetic peptides in multiple indications associated with… read more here.
Keywords: apolipoprotein mimetic; interferon alpha; long term; ifn ... See more keywords
Apolipoprotein Mimetic Peptides: An Emerging Therapy against Diabetic Inflammation and Dyslipidemia
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11050627
Abstract: Obesity has achieved epidemic status in the United States, resulting in an increase in type 2 diabetes mellitus, dyslipidemia, and cardiovascular disease. Numerous studies have shown that inflammation plays a key role in the development… read more here.
Keywords: apolipoprotein mimetic; mimetic peptides; emerging therapy; peptides emerging ... See more keywords