Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.04.038
Abstract: Deficient apoptosis of activated T cells can result in immunological disorders. Molecules associated with energy and metabolisms are suggested to be involved in pathogenesis of immune diseases, but remain uninvestigated. In the present study we… read more here.
Keywords: apoptosis activated; activated cells; monophosphate activated; adenosine monophosphate ... See more keywords
Sesamin Induces MCL-1-Dependent Apoptosis in Activated T Cells and Ameliorates Experimental Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.116753
Abstract: Sesamin, a natural lignan derived from Sesamum indicum, has been reported to possess anti-inflammatory and pro-apoptotic properties. However, its effect on T cell-mediated diseases and the underlying molecular mechanisms remain unclear. In this study, we… read more here.
Keywords: sesamin; mcl dependent; activated cells; apoptosis activated ... See more keywords