lncRNA expression profiles related to apoptosis and autophagy in peripheral blood mononuclear cells of patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12913
Abstract: Long noncoding RNAs (lncRNAs) are >200‐bp molecules that do not generally code for proteins. Human lncRNAs have well‐characterized roles in gene expression regulation, particularly with regard to protein‐coding genes, and their dysregulation has been linked… read more here.
Keywords: related apoptosis; apoptosis autophagy; peripheral blood; expression ... See more keywords
Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2723
Abstract: Hepatocellular carcinoma (HCC) is a devastating and highly metastatic cancer worldwide. Metformin (MET) is the priority drug for treatment of type 2 diabetes; however, it possesses multiple biological effects like anticancer and hepatoprotective activity. Herein,… read more here.
Keywords: apoptosis; pi3k akt; apoptosis autophagy; aloin met ... See more keywords
Blue light induces apoptosis and autophagy by promoting ROS‐mediated mitochondrial dysfunction in synovial sarcoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5664
Abstract: Synovial sarcoma (SS) has limited treatment options and there is an urgent need to develop a novel therapeutic strategy to treat SS. Blue light (BL) has been shown to inhibit the growth of several cancer… read more here.
Keywords: light induces; apoptosis autophagy; blue light; induces apoptosis ... See more keywords
Bufalin induces apoptosis and autophagy via the Ca2+/CaMKKβ/AMPK/Beclin1 signaling pathway in osteosarcoma cells.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12021
Abstract: Bufalin, a major cardiotonic compound of the traditional Chinese medicine Chanshu has been used for cancer treatment for several years. However, the molecular mechanisms of Bufalin-induced autophagy in osteosarcoma (OS) is not fully understood. In… read more here.
Keywords: ampk beclin1; apoptosis autophagy; bufalin; bufalin induced ... See more keywords
MicroRNA‐494 regulates high glucose‐induced cardiomyocyte apoptosis and autophagy by PI3K/AKT/mTOR signalling pathway
Sign Up to like & getrecommendations! Published in 2023 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14311
Abstract: Diabetic cardiomyopathy (DCM) is one of the major cardiovascular complications of diabetes. However, the mechanism of DCM is not fully understood. Studies have confirmed that certain microRNAs (miRNAs/miRs) are key regulators of DCM. The aim… read more here.
Keywords: microrna 494; high glucose; cardiomyocyte apoptosis; apoptosis autophagy ... See more keywords
Atractylodin induces oxidative stress‐mediated apoptosis and autophagy in human breast cancer MCF‐7 cells through inhibition of the P13K/Akt/mTOR pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23081
Abstract: This study aimed to determine the apoptosis and autophagy‐inducing mechanism of atractylodin in human breast cancer MCF‐7 cells. The molecular mechanism of anticancer activity of atractylodin was confirmed by assessing the levels of reactive oxygen… read more here.
Keywords: mcf; apoptosis autophagy; breast cancer; human breast ... See more keywords
Dihydroartemisinin induces apoptosis and autophagy‐dependent cell death in cholangiocarcinoma through a DAPK1‐BECLIN1 pathway
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DOI: 10.1002/mc.22893
Abstract: Cholangiocarcinoma (CCA) is a very aggressive cancer arising from the malignant transformation of cholangiocytes. Intrahepatic CCA is associated with reactive inflammation and intense fibrosis of the hepatobiliary tract. Dihydroartemisinin (DHA), the active compound found in… read more here.
Keywords: apoptosis autophagy; cell death; dapk1; cca ... See more keywords
Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Phytotherapy Research"
DOI: 10.1002/ptr.7738
Abstract: Regulated cell death (RCD) refers to programmed cell death regulated by various protein molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis. Accumulating evidence has recently revealed that RCD subroutines have several links to many… read more here.
Keywords: cell death; cell; apoptosis autophagy; plant ... See more keywords
Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy
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DOI: 10.1002/wrna.1584
Abstract: Osteoarthritis (OA) is a bone and joint disease characterized by progressive cartilage degradation. In the face of global trends of population aging, OA is expected to become the fourth most common disabling disease by 2020.… read more here.
Keywords: new regulatory; regulatory code; apoptosis autophagy; chondrocyte ... See more keywords
Potential applications of N6‐methyladenosine modification in the prognosis and treatment of cancers via modulating apoptosis, autophagy, and ferroptosis
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DOI: 10.1002/wrna.1719
Abstract: N6‐methyladenosine (m6A) is one of the most abundant modifications determining the fate of RNA. Currently, m6A modification is tightly connected with tumorigenesis and presents novel promise in clinical applications. Regulated cell death (RCD) is a… read more here.
Keywords: autophagy ferroptosis; modification; m6a; apoptosis autophagy ... See more keywords
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of toxicology"
DOI: 10.1007/s00204-021-03122-z
Abstract: Cannabidiol (CBD) is a constituent of Cannabis sativa without psychotropic activity, whose medical benefits have been recognised. However, little is known about the potential toxic effects of CBD on reproductive health. Placental development involves tightly… read more here.
Keywords: cannabidiol disrupts; htr svneo; invasion; apoptosis autophagy ... See more keywords