TSPAN8 alleviates high glucose‐induced apoptosis and autophagy via targeting mTORC2
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DOI: 10.1002/cbin.11870
Abstract: TSPAN8 mediates signal transduction from extracellular cues and regulates cell development, activation, growth, and motility. However, whether TSPAN8 is involved in the progression of diabetic nephropathy (DN) remains unclear. This study aimed to explore the… read more here.
Keywords: tspan8; apoptosis; apoptosis cells; high glucose ... See more keywords
Cholestane glycosides from Ornithogalum saundersiae bulbs and the induction of apoptosis in HL-60 cells by OSW-1 through a mitochondrial-independent signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1252-4
Abstract: A search for cytotoxic cholestane glycosides from Ornithogalum saundersiae bulbs resulted in the isolation of three new OSW-1 analogues (1–3), a new cholestane bisdesmoside (4), a 5β-cholestane diglycoside (5), and four new 24(23 → 22)-abeo-cholestane glycosides (6–9),… read more here.
Keywords: glycosides ornithogalum; cholestane glycosides; ornithogalum saundersiae; cholestane ... See more keywords
Exosomes derived from calcium oxalate-treated macrophages promote apoptosis of HK-2 cells by promoting autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2012622
Abstract: ABSTRACT Calcium oxalate (CaOx) crystals are the main component of kidney stones. Macrophages have the function of eliminating these crystals, and the underlying mechanism remains unclear. Here, we attempted to determine the role of macrophage-derived… read more here.
Keywords: caox exo; caox; treatment; treated macrophages ... See more keywords
Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2040875
Abstract: ABSTRACT To observe the role of transforming growth factor beta-activated kinase 1 (TAK1)/p38 MAPK/TGF-β1 signal pathway plays in oxidative stress and apoptosis in human renal tubular epithelial cells (HK-2) under high glucose induction. HK-2 cells… read more here.
Keywords: transforming growth; apoptosis; apoptosis cells; high glucose ... See more keywords
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2912276
Abstract: Background Abnormal Smad7 expression can lead to apoptosis in different cell types. Previously, we found high expression of Smad7 in rat degenerative discs. However, the exact role of Smad7 in the apoptosis of disc cells… read more here.
Keywords: apoptosis; apoptosis cells; degenerative discs; human degenerative ... See more keywords
Biological Activity of Extracts from Differently Produced Blueberry Fruits in Inhibiting Proliferation and Inducing Apoptosis of HT-29 Cells
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DOI: 10.3390/foods11193011
Abstract: For several decades, people have been searching for natural substances of plant origin that, when introduced into the diet, could strengthen immunity, have anticancer properties, and support conventional therapy. The development of agriculture with the… read more here.
Keywords: proliferation; cultivation; biological activity; apoptosis cells ... See more keywords
Lactobacillus paracasei subsp. paracasei X12 Strain Induces Apoptosis in HT-29 Cells through Activation of the Mitochondrial Pathway
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DOI: 10.3390/nu15092123
Abstract: L. paracasei subsp. paracasei X12 was obtained from traditional cheese produced in northwestern China. In this study, we showed that whole peptidoglycan (WPG), extracted from L. paracasei subsp. paracasei X12, inhibited proliferation and induced apoptosis… read more here.
Keywords: paracasei x12; paracasei; apoptosis cells; paracasei subsp ... See more keywords