Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.087
Abstract: We investigated the effect of the modulation of Na/H exchanger 1 (NHE1) on apoptosis, differentiation, and chemoresistance in acute myeloid leukemia (AML) cells to evaluate the possibility of NHE1 modulation as a novel therapeutic strategy… read more here.
Keywords: leukemia cells; modulation; leukemia; apoptosis differentiation ... See more keywords
Combined inhibition of XIAP and autophagy induces apoptosis and differentiation in acute myeloid leukaemia.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17765
Abstract: Perturbations in autophagy, apoptosis and differentiation have greatly affected the progression and therapy of acute myeloid leukaemia (AML). The role of X-linked inhibitor of apoptosis (XIAP)-related autophagy remains unclear in AML therapeutics. Here, we found… read more here.
Keywords: inhibition xiap; xiap; apoptosis differentiation; autophagy ... See more keywords