Articles with "apoptosis ferroptosis" as a keyword



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Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3

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Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23467

Abstract: Exposure to nickel oxide nanoparticles (NiONPs), which have been widely produced and applied in industry, leads to adverse pulmonary and systemic effects. The aim of this study is to investigate the involvement of apoptosis and… read more here.

Keywords: apoptosis ferroptosis; nickel oxide; lung; oxide nanoparticles ... See more keywords
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Polypyrrole-iron phosphate-glucose oxidase-based nanocomposite with cascade catalytic capacity for tumor synergistic apoptosis-ferroptosis therapy

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Published in 2022 at "Chemical Engineering Journal"

DOI: 10.1016/j.cej.2021.131671

Abstract: Abstract Utilizing the synergistic effect of apoptosis and ferroptosis for tumor elimination is a promising and effective strategy. Herein, a novel PPy-FePO-GOx-PVA nanocomposite with cascade catalytic capacity was designed and fabricated for tumor synergistic apoptosis-ferroptosis… read more here.

Keywords: apoptosis ferroptosis; cascade catalytic; apoptosis; tumor ... See more keywords
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Phosphorescent rhenium(I) complexes conjugated with artesunate: Mitochondrial targeting and apoptosis-ferroptosis dual induction.

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Published in 2021 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2021.111537

Abstract: Cell death is essential for cancer, which can be induced through multiple mechanisms. Ferroptosis, a newly emerging form of non-apoptotic cell death, involves the generation of iron-dependent reactive oxygen species (ROS). In this study, we… read more here.

Keywords: rhenium complexes; ferroptosis; art; phosphorescent rhenium ... See more keywords
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Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice

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Published in 2022 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2022.136579

Abstract: Intracerebral hemorrhage (ICH) is a fatal health problem which lacks effective treatment. The apoptosis caused by hematoma constituents, and the ferroptosis due to iron overload, are prominent contributors of neurologic impairment after ICH. Targeting cell… read more here.

Keywords: ferroptosis; vilda; ferroptosis following; apoptosis ferroptosis ... See more keywords

Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway.

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2036909

Abstract: The study aimed to explore the effects of local anesthetic bupivacaine on bladder cancer cells in vivo and in vitro. The cytotoxicity was detected by MTT assay. Apoptosis was measured by Hoechst 33342 staining and… read more here.

Keywords: apoptosis ferroptosis; bupivacaine; bladder cancer; pi3k akt ... See more keywords
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Organelle-Specific Mechanisms in Crosstalk between Apoptosis and Ferroptosis

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Published in 2023 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2023/3400147

Abstract: Apoptosis has been extensively studied, whereas ferroptosis is a newly discovered form of regulated cell death that involves iron-dependent accumulations of lipid hydroperoxides. While these two cell death mechanisms were initially believed to be mutually… read more here.

Keywords: organelle specific; apoptosis; crosstalk apoptosis; apoptosis ferroptosis ... See more keywords
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Yiqi Chutan Formula Reverses Cisplatin-Induced Apoptosis and Ferroptosis of Skeletal Muscle by Alleviating Oxidative Stress

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Published in 2023 at "Integrative Cancer Therapies"

DOI: 10.1177/15347354231172117

Abstract: Background: Cisplatin is a widely used anticancer drug in clinic, but it has a damaging effect on skeletal muscle cells. Clinical observation showed that Yiqi Chutan formula (YCF) had a alleviating effect on cisplatin toxicity.… read more here.

Keywords: oxidative stress; apoptosis ferroptosis; muscle; cisplatin ... See more keywords
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Sodium thiosulfate through preserving mitochondrial dynamics ameliorates oxidative stress induced renal apoptosis and ferroptosis in 5/6 nephrectomized rats with chronic kidney diseases

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Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0277652

Abstract: Chronic kidney disease (CKD) progression may be evoked through dysregulated mitochondrial dynamics enhanced oxidative stress and inflammation contributing to high cardiovascular morbidity and mortality. Previous study has demonstrated sodium thiosulfate (STS, Na2S2O3) could effectively attenuate… read more here.

Keywords: apoptosis; kidney; oxidative stress; apoptosis ferroptosis ... See more keywords

Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice

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Published in 2022 at "Neuroscience Letters"

DOI: 10.2139/ssrn.4034641

Abstract: Intracerebral hemorrhage (ICH) is a fatal health problem which lacks effective treatment. The apoptosis caused by hematoma constituents, and the ferroptosis due to iron overload, are prominent contributors of neurologic impairment after ICH. Targeting cell… read more here.

Keywords: apoptosis ferroptosis; ferroptosis following; ferroptosis; intracerebral hemorrhage ... See more keywords
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Label-Free Classification of Apoptosis, Ferroptosis and Necroptosis Using Digital Holographic Cytometry

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Published in 2020 at "Applied Sciences"

DOI: 10.3390/app10134439

Abstract: Apoptosis, ferroptosis and necroptosis are three distinct forms of programmed cell death. Each of these pathways can be exploited to terminate cancer cells. One promising therapeutic strategy is to activate alternative programmed cell death pathways… read more here.

Keywords: apoptosis ferroptosis; ferroptosis necroptosis; cell death; apoptosis ... See more keywords
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Artemisinin Derivatives Inhibit Non-small Cell Lung Cancer Cells Through Induction of ROS-dependent Apoptosis/Ferroptosis

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Published in 2021 at "Journal of Cancer"

DOI: 10.7150/jca.57054

Abstract: Non-small cell lung cancer (NSCLC) is one of the major cancer-related causes of morbidity and mortality worldwide. Despite the progress in lung cancer treatment, there is still an urgent need to discover novel therapeutic agents… read more here.

Keywords: lung cancer; ferroptosis; artemisinin derivatives; cancer ... See more keywords