Homocysteine facilitates endoplasmic reticulum stress and apoptosis of hepatocytes by suppressing ERO1α expression via cooperation between DNMT1 and G9a.
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DOI: 10.1002/cbin.11805
Abstract: Endoplasmic reticulum (ER) stress and apoptosis play a critical role in liver injury. Endoplasmic reticulum oxidoreductase 1α (ERO1α) is an oxidase that exists in the luminal side of the ER membrane, participating in protein folding… read more here.
Keywords: apoptosis; dnmt1 g9a; stress apoptosis; apoptosis hepatocytes ... See more keywords